Pulmonary Aspergillus infections are caused by the ubiquitous fungus mold when spores found in compost, dust, and plant material inhaled. Manifestation of disease is represented a delicate balance between host pathogen interactions, making infection more commonly observed immunocompromised individuals. Chronic cavitary pulmonary aspergillosis (CCPA) subtype Aspergillosis associated with history...

BACKGROUND/AIM To describe a case of invasive orbital aspergillosis and evaluate treatments and outcomes. METHODS A case report and review of orbital aspergillosis treatment with voriconazole in the English language literature. CONCLUSION Amphotericin B with debridement is the current standard of care for orbital aspergillosis; however, its prognosis is unfavorable. When compared to amphote...

Aspergillosis is a fungal disease characterized by invasive and noninvasive forms. Non-invasive aspergillosis usually affects a normal host, appearing either as an allergic reaction or a cluster of fungal hyphae. With the advent of intensive chemotherapeutic regimens, AIDS epidemic, solid organ and bone marrow transplantation, the prevalence of invasive aspergillosis has increased dramatically ...

BACKGROUND The study objectives were: 1) to report on invasive aspergillosis patients in a hematology department; and 2) to estimate its incidence according to the hematologic diagnosis. DESIGN AND METHODS A prospective survey of invasive aspergillosis cases was undertaken between January 2004 and December 2009 in the hematology department of a university hospital. Meetings with clinicians, m...

OBJECTIVES Fungal infections represent 5% of infections in renal transplant recipients. Candidiasis is the most frequent, followed by aspergillosis and cryptococcosis. Invasive aspergillosis is severe and has a poor prognosis, but recent series focused on outcomes are scarce in the literature. We analyzed invasive aspergillosis cases in a cohort of kidney transplant recipients and suggest that ...

endocarditis due to aspergillus infection is a rare complication in patients with hematological malignancies. here, we present a case of aspergillus endocarditis in a patient with acute myeloid leukemia (aml) successfully treated with antifungal therapy and surgical treatment. the patient was a 51 years old male, a known case of aml who was admitted to our medical center for evacuating his valv...

Tracheobronchial aspergillosis mainly involves the trachea, primary bronchus and segmental bronchus. the main symptoms including dyspnea, asthma and cough [1]. Based on clinical, bronchoscopic, and pathological presentations, Kramer and coworkers proposed a classification of tracheobronchial aspergillosis, they distinguished saprophytic, allergic, and invasive tracheobronchial aspergillosis (IT...

ASPERGILLOSIS IN CLINICAL CONTEXT Aspergillosis is a fungal infection that can assume a broad spectrum of clinical forms depending on immune status and the presence of underlying lung diseases, ranging from allergic bronchopulmonary aspergillosis to aspergilloma and also to the invasive aspergillosis forms that are a major cause of mortality in severely immunocompromised patients. Pulmonary asp...

The authors report four autopsy cases of previously healthy children with dengue shock syndrome complicated with infection-associated hemophagocytosis and invasive aspergillosis. Hemophagocytosis is confirmed by histopathology of autopsied reticuloendothelial organs. All four children were identified to have invasive aspergillosis by histopathology and three cases were positive on fungal cultur...

We describe an interesting case of severe asthma who was not showing satisfactory response to standard treatment. Investigations revealed him to be suffering from allergic bronchopulmonary aspergillosis (ABPA). After starting systemic steroids he showed marked improvement initially only to have recurrent symptoms within a year. He was investigated further and found to have chronic pulmonary asp...