introduction: ascorbic acid (aa) acts as an antioxidant in the central nervous system (cns) of the mammalians. it is released from the some nerve ending together with neurotransmitters. the results have shown that ascorbic acid could affect learning as well as memory. in this study, we examined the effect of icv injection of ascorbic acid on learning and memory by morris water maze. method: in ...

The instability of ascorbic acid in weakly acid solutions has recently been shown to be due to the copper content of the solutions (1). By strict elimination of copper, solutions of ascorbic acid are stable below pH 7.6. The preparation of copper-free reagents, however, is not very practical and in analytical procedures would not eliminate copper contamination from the materials analyzed. The u...

1. A study was undertaken to investigate the distribution of ascorbic acid between various cellular components of blood, in normal individuals, and its relation to the plasma concentration. Forty-one unsupplemented individuals and sixteen supplemented (2 g/d for 5 d) individuals were studied. 2. Granulocytes, mononuclear leucocytes, platelets and erythrocytes were separated by differential sedi...

A recent finding from this laboratory indicated that the incubation in vitro of purified xanthine oxidase with trace amounts of l-ascorbic acid resulted in a marked inhibition of the enzymatic activity (1, 2). Since the physiological mode’of action of Z-ascorbic acid is still obscure, it seemed desirable to determine whether ascorbic acid would, in the intact animal, exert a similar effect on x...

Skin-lightening agents such as kojic acid, arbutin, ellagic acid, lucinol and 5,5′-dipropylbiphenyl-2,2′-diol are used in ‘anti-ageing’ cosmetics. Cases of allergic contact dermatitis caused by these skin-lightening agents have been reported (1, 2). Vitamin C and its derivatives have also been used in cosmetics as skin-lightening agents for a long time. Vitamin C in topical agents is poorly abs...

Drought is the most common environmental stress in vineyard occurs in soils with low water content, even in irrigation condition. To evaluate foliar spraying of ascorbic acid under drought stress, a research during 2012 to 2013 years in the natural environment, and one year after the establishment of the cuttings in clay loam soil was conducted. Cultivars with two-level white seedless and khosh...

The metabolic fate of l-ascorbic acid-1-(14)C and -6-(14)C has been investigated in two species in two genera of Vitaceae. Results suggest that ascorbic acid metabolism in the Vitaceae involves splitting the 6-carbon chain into 4- and 2-carbon fragments. The former, corresponding to C1 through C4 of ascorbic acid, is further oxidized to tartaric acid while the latter, corresponding to C5 and C6...

Various chemicals can have different effects on the properties of the cement slurry. In this paper, the different effects of L-ascorbic acid have been investigated on the important parameters of cement slurry made from class G oil well cement. These parameters included the amount of free fluid, rheological properties, Thickening Time, and compressive strength. Several cement slurries were made ...

25 The ATDC5 cell line exhibits a multistep process of chondrogenic differentiation analogous to 26 that observed during endochondral bone formation. Previous investigators have induced 27 ATDC5 cells to differentiate by exposing them to insulin at high concentrations. We have 28 observed spontaneous differentiation of ATDC5 cells maintained in ascorbic acid-containing 29 αMEM. A comparison of ...