Introduction: Prenatal stress has deleterious effects on the development of the brain and is associated with behavioral and psychosocial problems in childhood and adulthood. This study aimed to determine the protective effect of L-arginine on fetal brain under maternal stress. Methods: Twenty pregnant Wistar rats (weighting 200-230 g) were randomly divided into 4 groups (n=5 for each group). T...

objective: tthe objective of this study was to assess the efficacy and safety of sx (combination of yohimbine and l-arginine) in the treatment of erectile dysfunction (ed) methods: this trial was a 4-week, double blind study of parallel groups of patients with mild to moderate ed. forty married male patients with ed of mild-to-moderate severity were screened for the study entry;among them, thos...

The paper presents comparative data on the effectiveness of complex treatment acute condyloma anogenital region (n = 105). Destruction genital warts was performed surgically, preceded by immunomodulatory and antiviral systemic therapy local with antiseptic measures hyaluronic acid, which continued in postoperative period. Patients first group 70) were added to drug - nitrogen donor L arginine. ...

introduction: the role of ovarian hormones and nitric oxide (no) on oxidative damage in brain tissues as well as learning and memory has been widely investigated.the present study was carried out to evaluate the effect of the precursor of no, l-arginine on learning and brain damage due to oxidative stress in ovariectomized (ovx) rats.methods: thirty -two rats were divided into four groups: 1) s...

Abstract Key message On calcareous soil, European beech roots prefer organic nitrogen, but only arginine and not glutamine or inorganic nitrogen. Nitrogen (N) acquisition is a major factor determining the processes mechanisms involved in tree productivity, development, competitiveness. However, few studies have investigated changes N capturing with age. We conducted 15 incubation experiments to...

introduction: nitric oxide (no) is a neuronal messenger molecule in the central nervous system, which is generated from l-arginine by nitric oxide synthase (nos) and involves in many important opioid-induced effects. our previous studies revealed that cuminum cyminum interestingly reduces morphine sensitization, tolerance and dependency in male mice. therefore, in the present study, the effect ...

The aim of the work is to study pharmacological substances that play a role eNOS expression regulators in modification lead intoxication effects experiment. Materials and methods. In experiment, linear male rats same age were used: intact with (120 heads). design was following: group 1 – control; 2 acetate solution; 3 + L-nitroarginine methyl ester; 4 5 L-arginine; 6 L-arginine. research carrie...

  The involvement of nitric oxide (NO) in the reinforcing properties of opiate reward was studied by examining the effect of a NO precursor (L-arginine) and a NO synthase inhibitor (L-NAME) on the rate of intravenous self-administration of morphine. This experiment was investigated in male albino Sprague Dawley rats (300 ± 50 g). At doses of 5 and 10 mg/kg (i.p.), L-arginine decreased morphine ...

This study aimed to examine whether a single ingestion of arginine activates the mammalian target rapamycin complex 1 (mTORC1) in rat fast- and slow-twitch skeletal muscles. In first experiment, rats were orally administered (3 or 10 mmol/kg body weight) water. The plantaris, gastrocnemius, soleus muscles excised h after administration. Immunoblot analysis showed that administration with higher...

Aim: Silicosis has long been recognized as an important occupational lung disease that is included in the group of pneumoconiosis. As already well-known silicosis a progressive pneumoconiosis characterized by fibrosis lungs. Also, chronic exposure to silica may cause obstructive pulmonary disease, emphysema, cancer, and fibrosis. Asymmetric dimethyl arginine (ADMA), symmetric (SDMA), L-NMMA (NG...