Background: In Himalayas, particularly Jammu and Kashmir, where 85% of people depend on agriculture and allied sectors, 70% of agriculture is rain-fed. While the Himalayas, highly seismic, contribute highest in sediment transported to the world oceans, surface soil is under threat due to erosion, and Rajouri district in western Himalayas is no exception. Various factors, especially land use pat...

BACKGROUND The intranasal (IN) administration of epinephrine could be an alternative route for anaphylaxis treatment. Although IN epinephrine absorption has been demonstrated in animals, such data in humans are still lacking. OBJECTIVE To study the pharmacokinetics of IN epinephrine absorption in humans. METHODS Each healthy adult (n = 5) was administered IN saline, IN epinephrine at variou...

Growing evidence from field studies has linked daily stressors to dysregulated patterns of diurnal cortisol. Less is known about whether naturally-occurring positive events in everyday life are associated with diurnal cortisol. The objectives of this study were to evaluate daily positive events as predictors of between-person differences and within-person (day-to-day) variations in diurnal cort...

PURPOSE To evaluate cancer detection with targeted biopsy of the prostate performed on the basis of high-frequency Doppler ultrasonographic (US) imaging findings versus cancer detection with a modified sextant biopsy approach with laterally directed cores. MATERIALS AND METHODS Sixty-two patients were prospectively evaluated with gray-scale, color, and power Doppler transrectal US performed w...

The Static-99 is a widely used actuarial risk assessment instrument. Various international validation studies have found satisfactory to good predictive validity for the Static-99, with the area under the curve (AUC) between 59% and 95%. This study is the first evaluation of the predictive accuracy of the Static-99 among sex offenders in Switzerland. The Static-99 scores of 69 violent/sex offen...

Due to their secretive habits, predicting the pattern of spatial distribution of small carnivores has been typically challenging, yet for conservation management it is essential to understand the association between this group of animals and environmental factors. We applied maximum entropy modeling (MaxEnt) to build distribution models and identify environmental predictors including bioclimati...

As part of "liquid biopsy," lots of literature indicated the potential diagnostic value of circulating cell-free DNA (cfDNA) in the management of prostate cancer (PCa). However, the literature on the accuracy of cfDNA detection in PCa has been inconsistent. Hence, we performed this meta-analysis to assess the diagnostic value of cfDNA in PCa. A total of 19 articles were included in this analysi...

To understand enzyme functions, identifying the catalytic residues is a usual first step. Moreover, knowledge about catalytic residues is also useful for protein engineering and drug-design. However, to experimentally identify catalytic residues remains challenging for reasons of time and cost. Therefore, computational methods have been explored to predict catalytic residues. Here, we developed...

achieving the self-sufficiency in producing agricultural crops and decreasing the pressure on the available water resources need determining the fertile places for cultivation based on the suitable evaluating indices. in this research, the prioritization of different township in sistan and blouchestan province for onion cultivation, as one of the most important production in the province, was c...

BACKGROUND AND PURPOSE Falls sustained by older adults are an increasing health care issue. Early identification of those at risk for falling can lead to successful prevention of falls. Balance complaints are common among individuals who fall or are at risk for falling. The purpose of this study was to evaluate the clinical utility of a multifaceted balance protocol used for fall risk screening...