There is a substantial evidence that large quantities of melatonin are produced in gastrointestinal tract, however, is still unclear which is the role of melatonin in digestive system in human physiology and pathophysiology. In the present study we investigated urinary excretion of a main melatonin metabolite, 6-sulphatoxymelatonin, in patients with irritable bowel syndrome (IBS). The investiga...

BACKGROUND Psychological disorders have been associated with irritable bowel syndrome (IBS) for decades in the absence of other objective etiology. However, such associations are also evident in other chronic diseases with more clearly defined pathogenesis such as ulcerative colitis. In this study, we examined the prevalence and severity of psychological disorders among IBS and ulcerative colit...

background: various psychological interventions were considered as part of the treatments of irritable bowel syndrome. however, the effectiveness of coping strategies in improving symptoms of this disease remains unclear. the objective of this study was to assess the effects of coping strategies training in treatment of irritable bowel syndrome (ibs). methods: in this randomized, placebo-contro...

OBJECTIVE To compare the post-infectious irritable bowel syndrome (PI-IBS) and none post-infectious irritable bowel syndrome (NPI-IBS) clinically and experimentally. METHODS From May 2013 to January 2015, eighty-nine patients with irritable bowel syndrome (IBS)were recruited in the internal department of the affiliated hospital of Shandong University of Traditional Chinese Medicine. The clini...

BACKGROUND/AIMS Psychosocial stressors likely play an important role in irritable bowel syndrome (IBS). The association between IBS and post-trau-matic stress disorder (PTSD) in non-minorities has been described. Our aim was to investigate the potential association between IBS and PTSD in an urban African American population. METHODS Our institution maintains a longitudinal population-based s...

Irritable bowel syndrome (IBS) is a functional digestive disorder that affects medical students at higher rate than the general population. Intern doctors are most affected class by IBS among students. Determining prevalence of and associated risk factors essential for taking preventive measures. We aimed to investigate predictors intern in this study. This study was conducted using an online s...

Irritable bowel syndrome (IBS), a chronic disorder, greatly impacts the lives of those affected. Approximately one quarter of the North American population suffers from this condition that includes abdominal pain, discomfort and alterations in normal bowel function. Constipation-subtype IBS (IBS-C) is often found to be a prevalent subtype; however, a lack of knowledge and effective treatment op...

Background and Objectives: Gastrointestinal disorders like irritable bowel syndrome (IBS) and constipation can affect the quality of life and various factors play a role in these disorders. The aim of this study was to investigate the environmental factors related to these problems among Iranian male university students. Materials and Methods: The study was conducted on 186 male students at ...

The aim of this study was to investigate the correlation between anxiety-depression status and cytokines in diarrhea-predominant irritable bowel syndrome (IBS-D). IBS-D patients were divided into an anxiety-depression IBS-D group and a non-anxiety-depression IBS-D group. Patients without IBS, anxiety or depression were selected as the control group. Scoring was performed using the self-rating a...