Several therapeutic effects including diuretic, anti-pyretic and anti-scurvy have been reported for Portulaca oleracea. In previous studies the analgesic, anti-inflammatory, anti-hypertensive, anti-oxidant, muscle relaxant effects and neuropharmacological effects of the aqueous extract of Portulaca oleracea have been demonstrated on experimental animals. In the present study the antitussive eff...

Several therapeutic effects including diuretic, anti-pyretic and anti-scurvy have been reported for Portulaca oleracea. In previous studies the analgesic, anti-inflammatory, anti-hypertensive, anti-oxidant, muscle relaxant effects and neuropharmacological effects of the aqueous extract of Portulaca oleracea have been demonstrated on experimental animals. In the present study the antitussive eff...

BACKGROUND Several observations have suggested that anandamide, an endogenous cannabinoid ligand, plays an important role in the modulation of cough sensitivity. However, it is unknown whether the anandamide membrane transporter plays a role in this modulation. To test this hypothesis, we investigated the effects of VDM11, an anandamide membrane transporter inhibitor, on capsaicin- and anandami...

Cough is the most common symptom of respiratory diseases. When cough becomes serious, opioids are effective, but they have side effects like sedation, constipation. Therefore, there is a need to have effective antitussive agent which do not have respiratory depressant activity. The present study was carried out to evaluate antitussive activity of Glycyrrhiza glabra and Adhatoda vasica using a c...

Several therapeutic effects including hypnotic, antispasmodic, treatment of abdominal and chest pain and strengthening the heart have been described for the flowers of Rosa damascena. North American Indian tribes use a decoction of the roots obtained from the Rosa damascena plant as a cough remedy and to treat eye problem. Therefore, in the present study the antitussive effect of this plant in ...

Nonproductive cough is a frequent and distressing symptom in patients with lung cancer, and it is not even relieved by palliative chemotherapy. A double-blind, randomized clinical trial regarding the treatment of nonproductive cough was performed in 140 adults with primary lung cancer or metastatic cancer of the lungs. The therapeutic efficacy and the tolerability of a 7-day treatment with levo...

26 The caudal nucleus tractus solitarii (NTS) is the main central station of cough-related 27 afferents and a strategic site for the modulation of the cough reflex. The similarities 28 between the characteristics of central processing of nociceptive and cough-related inputs 29 led us to hypothesize that galanin, a neuropeptide implicated in the control of pain, 30 could also be involved in the ...