Andrographis paniculata nees (Acanthaceae) is a medicinal plant traditionally used for the treatment of anti-inflammatory, antibacterial, antioxidant, antiparasitic, antispasmodic, antidiabatic, anti carcinogenic, antipyretic, antidiarrhoeal, hepatoprotective, nematocidal, antiHIV and several infectious diseases ranging from malaria to dysentery. The plant is widely used in ayurvedic and homeop...

Spices are often used as dietary components to improve color, aroma, palatability and acceptability of food. Most spices are fragrant, aromatic and pungent.1 Spices and herbs, grown widely in various regions of the world, have been used for several purposes since ancient times – in folk medicine as antiscorbutic, antispasmodic, tonic, carminative agents against bronchitis, ulcers and as diureti...

Drug-induced hepatotoxicity is an important cause of hepatocellular injury. Hepatic necrosis may range from asymptomatic elevations in transaminases to fulminant hepatic failure and death. Alverine is an antispasmodic drug which is especially used in patients with irritable bowel syndrome. Only a few cases of alverine associated hepatotoxicity have been reported previously. We present the case ...

Justicia adhatoda L. which belongs to the family of Acanthaceae contains alkaloids like vasicine, vasicinone and deoxyvasicine. These alkaloids give the plant its expectorant activity, antispasmodic, antiseptic and antihelmintic properties. Hence, in the present investigation attempts were made to isolate and characterise alkaloids from callus and suspension cultures of J. adhatoda. Alkaloids w...

Pharmacognosy Research,2022,14,4,492-498.DOI:10.5530/pres.14.4.71Published:October 2022Type:Original ArticleAuthors:Adaobi C. Ezike, Nwoyi N. Bassey, Emenike Amah, Daniel U. Nwankpa, Aniebiet E. Samuel, and John O. Medewase Author(s) affiliations:Adaobi Ezike*, Department of Pharmacology Toxicology, Faculty Pharmaceutical Sciences, University Nigeria, Nsukka, Enugu, NIGERIA. Abstract:Background...

Cardiospermum halicacabum used in Ayurveda has been investigated for various pharmacological actions in a number of experimental animal models. On central nervous system the decoction of the plant showed sedative effect. It exhibited significant analgesic and anti-inflammatory activities. The drug also showed vasadepressant activity which is considered to be transcient in nature. In vitro studi...

Table 1. Symptom – Based Treatment of Irritable Bowel Syndrome Pain Predominant Diarrhea Predominant Constipation Predominant Antispasmodic Agents  Dicycloverine (Bentyl)  Mebeverine Tricyclic Antidepressants  Amitriptyline Antidiarrheal Agents  Loperamide (Imodium)  Cholestyramine (questran) Serotonin (5-HT3) antagonist  Alosetron (Lotronex)  Ondansetron (Zofran) Serotonin (5-HT4) Agoni...