Melanoma is a highly lethal type of cancer that has increased in incidence recent decades. Nevertheless, current therapies lack effectiveness and have disabling side effects, which calls for new therapeutic strategies. Norcantharidin (NCTD) an acid derivative isolated from natural blister beetles with potential antitumor activity. However, its use restricted due to solubility limitations. To ta...

Abstract Background This research was performed to synthesize nanophytosome-loaded high phenolic fraction (HPF) from Juniperus polycarpos fruit extract and investigate its antiproliferation effects against breast cancer in mice model. Results The HPF synthesized. trial conducted determine the possible toxic of synthesized nanophytosomes. anticancer, pro-apoptotic, antioxidative activities nanop...