Jadomycins are natural products biosynthesized by the bacteria Streptomyces venezuelae which kill drug-sensitive and multidrug-resistant breast cancer cells in culture. Currently, the mechanisms of jadomycin cytotoxicity are poorly understood; however, reactive oxygen species (ROS)-induced DNA cleavage is suggested based on bacterial plasmid DNA cleavage studies. The objective of this study was...

Fenugreek (Trigonella foenum-graecum) typically called Methi is an annual herb belonging to own circle of relatives Fabaceae. It decreases the bad cholesterol stage reduces frame weight through lowering plasma triglycerides tri glycerides. thought have hypocholesterolemic, antioxidant potency, digestive stimulant movement, and hepatoprotective effect. anticarcinogenic, antioxidant, antibacteria...

Wounds are caused by skin injuries that damage the soft tissue. Wound healing is a dynamic process involves series of interconnected cellular and molecular processes result in restoration anatomic continuity function. Herbal therapy has been gaining popularity recently because plants' usefulness treating ailments with hardly any negative effects. Over years, variety plant items have developed u...

This study aimed to investigate the potency of silymarin (SMN) and melatonin (MEL) on restoring the pancreatic  cells in streptozotocin (STZ)-induced diabetic rats. Male Wistar rats were divided into five groups, including: control (C), untreated diabetic (D), SMN-treated diabetic (50 mg/kg, orally), MEL-treated diabetic (10 mg/kg, i.p.), and SMN plus MEL-treated diabetic rats. Diabetes was in...

The aim of the study was to evaluate the antioxidant and free radical scavenging properties and to determine the phenolic content of the ethanol extract from five Mentha species [M. longifolia (L.) Huds., M. piperita L., M. pulegium L., M. rotundifolia (L.) Huds., and M. spicata L.]. The antioxidant activities of the extracts were investigated with two different methods, 2,2’-diphenyl-1-picrylh...

This research aimed to explore the antioxidant potency of leaf extracts Syringodium isoetifolium seagrass. In this study, seagrass leaves were collected from local tribe’s source, dried and extracted with water, alcohol, hydro alcohols, acetone n-hexane. Phytochemical investigation on was performed using chemical gas chromatography-mass spectrometric techniques. It reveals that are enriched pha...

stability studies play a critical role in assuring product quality at all points in the vaccine life cycle. these studies used to determine vaccine expiry date and vaccine efficacy. accelerated stability and long term stability study performed for three batches of trivalent oral poliomyelitis vaccine (opv) and three batches of monovalent opv (type1) manufactured by razi institute. after samplin...

the therapeutic potential of crude extracts of aerial parts (stem, leaves and flowers) of tridax procumbens was screened for in vitro antioxidant potential and alpha amylase inhibitory action. the crude hydro-methanolic, aqueous and petroleum ether extracts were obtained by percolation-maceration method using 50% methanol, double distilled water and petroleum ether as solvents. phytochemical sc...