Carbon tetrachloride (CCl4), a hepatotoxic agent is widely used to study the toxic mechanisms in experimental animals. This study was carried out to establish the hepatoprotective measures of food preservative antioxidants butylated hydroxyanisole and butylated hydroxytolune (BHA, BHT) when mixed with food towards carbon tetrachloride (CCl4) intoxication (230 mg/ kg b wt/rat/day) in rat. Bioche...

The present study was undertaken in patients of ovarian malignancy to evaluate the status of oxidative stress and antioxidant defence mechanisms undergoing chemotherapy treatment. Circulating plasma lipid peroxides as malondialdehyde [MDA] and activities of the defensive enzymes (Superoxide Dismutase [SOD] and Catalase [CAT]) were measured. Blood samples were collected before treatment and with...

Cell culture data indicate that quercetin and catechin may affect the activity of phase II and antioxidant enzymes. However, little is known about the impact of dietary flavonoids in vivo. Therefore, the present study aimed to investigate the in vivo effects of the flavonoids quercetin and catechin on mRNA and activity levels of phase II enzymes glutathione-S transferase (GST) and NAD(P)H quino...

Diabetes mellitus (DM) causes not only hyperglycemia but oxidative stress, resulting mainly enhanced production of mitochondrial reactive oxygen species (ROS). Hyperbaric oxygen (HBO) treatments are applied various diseases including diabetic patients with unhealing foot ulcers, however, and also increases the formation of ROS. Recently, it has been reported that oxidative stress worsens many p...

Adaptation and defense responses are the consequences of exposure to drought stress in plants. Salicylic acid (SA) as a natural signaling molecule poses a significant impacts on various aspects of plant growth and development. This study investigates the effects of SA on carotenoids content, lipid peroxidation rate and antioxidant enzymes activities. A pot experiment was conducted using a facto...

this study investigated the influence of inoculation with an arbuscular mycorrhizal fungus (amf), glomus mosseae (nicol & gerd.) on growth and antioxidant enzyme activities (sod, cat, gupx) in shoots and roots of wheat (triticum aestivum l.) affected by three different levels of salt stress. the experiment was arranged as a factorial in randomized complete block design (rcbd) with three replicat...

background: withania somnifera l. dunal, (ashwagandha) belongs to the family solanaceae and is known as ‘indian ginseng’ in the traditional system of medicine. objectives: in the present investigation, comparative analysis was carried out between two different ecotypes of w. somnifera related to total soluble protein and antioxidant enzyme activity [catalase (cat), superoxide dismutase (sod) an...

Garcinia mangostana (GM) pericarp is an herbal medicine in the Thailand National Essential Drug List. GM and its major active constituent α-mangostin (MGS) exhibit several pharmacological properties, including anti-oxidative activity. Ulcerative colitis (UC) consequence of prolonged oxidative stress inflammation large intestine can result in extraintestinal manifestations (EIM) other ...

Psoriasis is one of the skin’s chronic inflammatory diseases. etiology isn’t exactly known. Recently, it has been suggested that imbalances in oxidant-antioxidant status happening because increase reactive oxygen species production (ROS) and/or deficient function regarding antioxidant system might be included psoriasis pathogenesis. The major goal to evaluate defense patients experiencing and o...

in this study the effect of salt stress on banding patterns of superoxide dismutase (sod), catalase (cat) and peroxidase (pox) in 18 genotypes of white common bean (phaseolus vulgaris l.) were examined under two levels of nacl )0 and 400 mm) stress. for each isozymic band the “density × area” scores on gels were evaluated by mcid software and considered as enzymatic activity. three isozymes wer...