OBJECTIVE To assess the health and economic burden of human papillomavirus (HPV)-related diseases (cervical cancer, cervical intraepithelial neoplasia (CIN) 1/2/3, and genital warts) in Singapore over a period of 25 years beginning in 2008. METHODS Incidence-based modeling was used to estimate the incidence cases and associated economic burden, with the assumption that age-stratified incidenc...

This paper provides a survey of methodological problems encountered in an assessment of the economic consequences of accidents in The Netherlands. A sound epidemiological basis for such calculations appears to be lacking due to inadequate data-registration systems. We also discuss some studies of the economic costs of injuries due to accidents for other countries, which have used either a preva...

Background The continuous use of biologic agents in the treatment of psoriasis has been reported to result in successful and sustained therapeutic effects and safety. However, some patients choose intermittent and repetitive treatment. Objective To determine the factors for selecting intermittent and repetitive ustekinumab treatment for the management of psoriasis. Methods From January 2011...

The Canadian Medical Association’s Healthcare Transformation initiative is an impressive example of the work being done to communicate the importance of the social determinants of health to the Canadian public. The communication element of this work is critical, given widely held beliefs that downplay the importance of the social determinants of health: “Despite much research indicating that hi...

INTRODUCTION Human papilloma virus (HPV) genotypes 6, 11, 16, and 18 impose a substantial burden of direct costs on the Italian National Health Service that has never been quantified fully. The main objective of the present study was to address this gap: (1) by estimating the total direct medical costs associated with nine major HPV-related diseases, namely invasive cervical cancer, cervical dy...

Human papillomavirus (HPV) infection is a common sexually transmitted infection that is often acquired at the onset of sexual activity. Risk factors include younger age at time of sexual debut, sexual behavior, intact foreskin, and immunologic status. Persistent infection with high-risk oncogenic HPV types (especially 16 and 18) is associated with cervical cancer, other anogenital diseases, as ...

INTRODUCTION An analysis was conducted to estimate the economic burden of insulin-related hypoglycemia in adults in Spain, derived from a novel concept developed for the UK known as the Local Impact of Hypoglycemia Tool. METHODS Costs per severe and non-severe hypoglycemic episode were calculated for patients with type 1 diabetes (T1DM) and type 2 diabetes (T2DM). The costs per episode were a...