Assay of f3-lactam antibiotics when used therapeutically in combination with aminoglycosides In 1977, Stevens and Young' reported the use of the cation-exchanger cellulose phosphate (CP) as an inactivator of aminoglycosides in serum samples which also contained a f8-lactam antibiotic. After inactivation of the aminoglycoside the /8-lactam antibiotic was subsequently determined in a mic-robiolog...

STUDY DESIGN Research OBJECTIVE.: The goal of this study was to investigate whether P. acnes infection of the intervertebral disc can be detected noninvasively by NMR spectroscopy. SUMMARY OF BACKGROUND DATA Microbiological studies of surgical samples suggest that a significant subpopulation of back pain patients may have occult disc infection with P. acnes bacteria. This hypothesis is furthe...

Silver nanoparticles (AgNPs) have been used as potential antimicrobial agents against resistant pathogens. We investigated the possible therapeutic use of AgNPs in combination with visible blue light against a multidrug resistant clinical isolate of Pseudomonas aeruginosa in vitro and in vivo. The antibacterial activity of AgNPs against P. aeruginosa (1×10(5) colony forming unit/mL) was investi...

Background: Campylobacter infections may lead to serious conditions, including septicemia or other invasive forms of the disease, which require rapid and accurate laboratory diagnosis and subsequently appropriate antimicrobial therapy. The aim of this study was to compare the species distribution and antimicrobial susceptibility pattern of Campylobacter spp. strains isolated from patients and f...

background: brucellosis, a zoonosis caused by four species of brucella, has a high morbidity. the major cause of brucellosis worldwide is brucella melitensis. medicinal plants are considered as new antibacterial sources that could replace conventional antibiotics in the treatment of antibiotic-resistant bacteria. the aim of this study was to evaluate the efficacy of some native plants, alone an...

Pseudomonas spp. has become increasingly recognized as an emerging opportunistic pathogen. A total of 80 isolates of Pseudomonas spp. were isolated from blood cancer patient from three tertiary hospitals in and around Tirupur and Erode (Dts). The pathogenic strains were subjected to antibiotic susceptibility testing by disk diffusion method. Ten different antibiotic discs were used to determine...

Background Antimicrobial resistance is an important factor threatening human health. It is widely accepted that antibiotic resistant bacteria such as Escherichia coli (E. coli) released from humans and animals into the water sources, can introduce their resistance genes into the natural bacterial community. Objective The aim of this study was to investigate the prevalence of blaTEM, blaCTX, b...