نتایج جستجو برای: antibacterial drug

تعداد نتایج: 625588  

Journal: :Antimicrobial agents and chemotherapy 2004
Bernd Hutter Christoph Schaab Sebastian Albrecht Matthias Borgmann Nina A Brunner Christoph Freiberg Karl Ziegelbauer Charles O Rock Igor Ivanov Hannes Loferer

We have generated a database of expression profiles carrying the transcriptional responses of the model organism Bacillus subtilis following treatment with 37 well-characterized antibacterial compounds of different classes. The database was used to build a predictor for the assignment of the mechanisms of action (MoAs) of antibacterial compounds by the use of support vector machines. This predi...

2016
Thomas J. Webster

Introduction: Bacterial antibiotic resistance has become one of the biggest threats to global health. In the United States alone, at least 2 million cases of illness and 23,000 of deaths are caused by antibioticresistant bacteria annually. The overuse of antibiotics is the most important factor responsible to the development of antibiotic resistance around the world [1]. To overcome bacterial d...

Journal: :Clinical Microbiology and Infection 2004

Journal: :International Journal of Infectious Diseases 2016

2010
Maria Sjölund-Karlsson Rebecca Howie Regan Rickert Amy Krueger Thu-Thuy Tran Shaohua Zhao Takiyah Ball Jovita Haro Gary Pecic Kevin Joyce Paula J. Fedorka-Cray Jean M. Whichard Patrick F. McDermott

We determined the prevalence of plasmid-mediated quinolone resistance mechanisms among non-Typhi Salmonella spp. isolated from humans, food animals, and retail meat in the United States in 2007. Six isolates collected from humans harbored aac(6')Ib-cr or a qnr gene. Most prevalent was qnrS1. No animal or retail meat isolates harbored a plasmid-mediated mechanism.

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