Several pathogenic or opportunistic bacteria have the ability to either induce or inhibit host cell apoptosis. The capacity to modulate cell pathways that result in the induction or delay of host cell apoptosis is considered to be an important bacterial virulence mechanism. These processes could be mediated by different host cell signaling pathways that are subverted by the bacteria. Pathogens ...

Introduction Increasing numbers of patients with immunodeficiencies, malignant diseases, advanced surgeries and prolonged stays in intensive care units are at risk for developing infections by enteric bacteria, which often are systemic (sepsis) and caused by multidrug resistance isolates. Intestinal bacteria provide also a constant antigenic stimulation for the synthesis of natural anti-carbohy...

abstract       background and objective: glycyrrhizaglabra l. is one of the most widely used medicinal herbs in golestan province that is known for its anti-inflammatory, carminative, antiviral, anti-infection and anti-ulcer properties in iranian traditional medicine. this study aimed to assess the anti-bacterial and anti-oxidative activity of g. glabrafrom the golestan province.         method...

Abstract Immune checkpoint inhibitors (ICI), such as anti-PD-1, have revolutionized cancer treatment. The use of antibiotics can lead to abnormal gut microbiome composition resulting in primary resistance ICI. However, the mechanism by which this occurs is poorly understood. Metagenomic analyses melanoma patient stool samples prior therapy revealed an association between clinical responses anti...