background: periodontitis and rheumatoid arthritis (ra) share a number of clinical and pathologic features, one of which is the presence of the tumor necrosis factor alpha (tnf-α)-induced bone resorption that is involved in the pathogenesis of both. objectives: to investigate the effect of tnf-α blockade on periodontal conditions in patients with active ra. method: the periodontal statuses of 3...

peperomia pellucida leaf extract was characterized for its anticancer, antimicrobial, antioxidant activities, and chemical compositions. anticancer activity of p. pellucida leaf extract was determined through colorimetric mtt (tetrazolium) assay against human breast adenocarcinoma (mcf-7) cell line and the antimicrobial property of the plant extract was revealed by using two-fold broth micro-di...

antibiotic guidelines have proven to be a simple and effective intervention to guide the choice of appropriate empiric antibiotic regimens. the goals of this study were to evaluate adherence to guidelines and streamlining of antibiotics. hospital records of hospitalized patients in infectious diseases ward imam khomeini hospital, tehran, iran, from may 2008 to september 2009 were reviewed. adhe...

background: the expanse of dendritic cells (dc) differentiation plays an important role in determining immune response. dc-based immunosuppressive drugs have notable side effects in increasing the risk of infectious diseases and cancers. g2013, as a novel anti-inflammatory and immunosuppressive agent, has been tested in experimental model of multiple sclerosis. the aim of this study was to cond...

urtica dioica is a perennial plant used as herbal medicine due to its many pharmacological and clinical effects. because of its antioxidant activity, it is widely used in traditional diabetes treatment but is also known as antimicrobial, anti inflammatory or anti prostate cancer agent. extensive studies have been conducted on different parts of this plant and their biological effects. here we r...

epilepsy is a neurological disease of the central nervous system. it is estimated that about 50-70 million people worldwide suffer from this chronic disorder and 20 to 30% are resistant to conventional anti-epileptic drugs. in the epilepsy therapeutic arena, there is real need for developing novel antiepileptogenesis treatments that offer a way to prevent the onset or the progression of the dis...

introduction: black pepper (piper nigrum l.) is one of the medicinal plants being used to prevent and manage stroke in persian medicine. current findings support its anti-inflammatory, radical scavenging and neuroprotective characteristics. in this study, we aimed to evaluate role of black pepper on functional and histopathological outcomes of stroke in an animal model of mcao. materials and me...

jasminum amplexicaule buch.-ham. (oleaceae) has been commonly used in the traditional medicine in dysentery, diarrhoea and bellyache in china. in the present work, the methanol extract of jasminum amplexicaule (jme) was examined for pharmacology on human colonic epithelial cell line t84 by the short-circuit current technique. the results showed that pretreatment of t84 cells with jme produced a...

atrial fibrillation (af) is a commonly encountered arrhythmia in our daily practice. every year a huge bulk of data is published about different management strategies, new antiarrhythmic drugs, anticoagulation protocols and ablation procedures in these patients. in this review article, we discuss different management strategies and new antiarrhythmic drugs as well as those commonly used. we wil...

background vitamin d (vit d) level may change variously in serums of patients undergoing anti-tuberculosis (anti-tb) therapy using antibiotics such as isoniazid and rifampin. objectives the current study aimed to evaluate all components of calcium (ca) regulatory agents in the six- month period of standard anti- tb therapy. patients and methods eight adults whose pulmonary tb had been diagnosed...