BACKGROUND Cutaneous leishmaniasis (CL) caused by Leishmania tropica is endemic in Kerman, southeastern Iran. While dogs have long been implicated as the main domestic reservoirs of L. infantum, etiological agent of zoonotic visceral leishmaniasis (ZVL), they can also carry L. tropica infection. The objective of the present study was to determine molecular identity and to evaluate histopatholog...

a clinical and epidemiological comparison of the cutaneous leishmaniasis was carried out among 100 victims of cutaneous leishmaniasis who were living in the villages of isfahan area, and 100 other patients of the lesions have been determined and analyzed. comparison of patients of the city with that of neighboring villages shows that both type of cutaneous leishmaniasis are prevalent in isfahan...

BACKGROUND To compare three molecular methods, PCR-RFLP for internal transcribed spacer, PCR sequencing and high resolution melting analysis shown reliable sensitivity and specificity for detecting Leishmania tropica as a model for cutaneous leishmaniasis (CL) as the perspective overview for scientific and economic approaches. METHODS This study was carried out between 2015 and 2016 in Leishm...

The mainstay therapy against leishmaniasis is still pentavalent antimonial drugs; however, the rate of antimony resistance is increasing in endemic regions such as Iran. Understanding the molecular basis of resistance to antimonials could be helpful to improve treatment strategies. This study aimed to recognize genes involved in antimony resistance of Leishmania tropica field isolates. Sensitiv...

More than 90% of patients infected with cutaneous leishmaniasis live in Afghanistan, the Middle East, Algeria, Brazil, and Peru. Cutaneous leishmaniasis in Iran is caused by Leishmania tropica and Leishmania major. Most skin lesions evolve from papular to nodular, to ulcerative form with a central depression surrounded by a raised indurate border. Some lesions persist as nodules or plaques. Mul...

background: leishmaniasis, especially cutaneous leishmaniasis, is considered an important health problem in many parts of iran including kharve, khorasan razavi province. cutaneous leishmaniasis is caused by various species of leishmania, each having a different secondary host. thus, identifying the parasites’ specie is of paramount importance for containment strategy planning. the morphologica...

Leishmaniasis is an infectious disease in form of visceral (VL), cutaneous (CL), and mucocutaneous (MCL) leishmaniasis. Immunocompromised patients have increased risk of Leishmania infection, especially in endemic areas for visceral leishmaniasis, where in the world HIV/VL coinfection has become endemic. The case here suffers from both AIDS and visceral-cutaneous leishmaniasis. We report an Ira...

the aim of this study was to measure the alterations in serum zinc (zn) copper (cu) and iron (fe) concentrations in patients with acute and chronic cutaneous leishmaniasis. serum zinc and copper were measured by flameless atomic absorption spectrophotometer and serum iron concentration was measured by the ferrozine method with commercial kits and assay was carried out by using an automatic anal...

cutaneous leishmaniasis may present with clinical presentation such as zosteriform, sporotrichoid and erysipeloid. the eczema variant has rarely been reported. we report a 27- year- old patient with atypical cutaneous leishmaniasis resembling eczema on the hand of a man in yazd province in the central of iran.