Conjugated linoleic acid (CLA) isomers have attracted significant attention due to their important physiological properties, which have been observed in humans. Many lactic acid bacteria (LAB) demonstrate the ability to produce CLA isomers (C18:2 cis-9, trans-11 and C18:2 trans-10, cis-12) from the linoleic acid (LA) present in milk or in synthetic media. CLA isomers can be synthesized in vitro...

Background Green tea, caffeine, conjugated linoleic acid (CLA), and branched chain amino acids (BCAA) have shown to individually improve body composition and metabolic rate in overweight and obese individuals. The purpose of this study was to investigate the effects of a multi-ingredient dietary supplement (MIDS) containing these ingredients on body composition, lipid profile, and metabolic rat...

Mice raised on a coconut oil (CO)-containing diet for 6 wk prior to the addition of conjugated linoleic acid (CLA) are more sensitive to CLAinduced body fat loss than mice raised on a soy oil (SO)-containing diet. Coconut oil is deficient in essential fatty acids. However the addition of linoleic acid to a CO-containing diet did not alter the enhanced sensitivity to CLA. The objective of this s...

and Implications Conjugated linoleic acid (CLA) improved carcass characteristics of pork by decreasing backfat and increasing fat hardness (firmness). CLA also improved the color of pork loin chops and patties both initially and over retail storage time. Combined, these carcass composition and sensory characteristic improvements could provide processors and consumers a more desirable product. T...

The process called biohydrogenation occurs mainly in ruminant animals and during it, unsaturated fatty acids, and particularly poly-unsaturated ones (linoleic and linolenic) coverts to a saturated form of stearic acid. For many years, the beneficial effects of biohydrogenation intermediate fatty acids like cis-9 trans-11 linoleic acid, the main natural isomer of conjugated linoleic acids (CLA),...

Conjugated linoleic acids (CLAs) are conjugated dienoic isomers of linoleic acid. Many people supplement their diets with CLAs to attempt weight loss, and the trans-10,cis-12 isomer (t10,c12-CLA) of CLA reduces adiposity in animal models and humans. However, CLA treatment in mice causes insulin resistance that has been attributed to the lipoatrophic state, which is associated with hyperinsuline...

The chemistry of conjugated fatty acids, specifically octadecadienoic acids (18:2; commonly referred to as conjugated linoleic acid, or CLA), has provided many challenges to lipid analysts because of their unique physical properties and the many possible positional and geometric isomers. After the acid-labile properties of CLAs during analytic procedures were overcome, it became evident that na...

Conjugated linoleic acid, better known as CLA, is a fatty acid derived from the required nutrient, linoleic acid. The major structural difference between linoleic acid (an 18 carbon, polyunsaturated fatty acid) and CLA, is that linoleic acid has double bonds at carbons 9 and 12 in a cis configuration (methylene interrupted), while CLA has numerous isomers without methylene interrupted conjugate...

BACKGROUND Conjugated linoleic acid (CLA) is reported to have weight-reducing and antiatherogenic properties when fed to laboratory animals. However, the effects of CLA on human health and, in particular, the effects of individual CLA isomers are unclear. OBJECTIVE This study investigated the effects of 3 doses of highly enriched cis-9,trans-11 (0.59, 1.19, and 2.38 g/d) or trans-10,cis-12 (0...