http://jra.sagepub.com/content/10/1/24 The online version of this article can be found at: DOI: 10.1177/1470320309104067 2009 10: 24 Journal of Renin-Angiotensin-Aldosterone System Manuel Labiós, Marcial Martínez, Francisco Gabriel, Victoria Guiral, Francisco Dasi, Belén Beltrán and Anna Muñoz patients: effects of eprosartan treatment Superoxide dismutase and catalase anti-oxidant activity in l...

The renin-angiotensin system plays a central role in the pathogenesis of cardiovascular disease. At the molecular and cellular levels, angiotensin II, the main effector peptide of the system, stimulates key components of atherosclerosis. Trials in animals and humans indicate that blocking renin-angiotensin system pathways decreases atherosclerotic plaque progression and ischemic events. This re...

Submit Manuscript | http://medcraveonline.com Abbreviations: RAS, renin angiotensin system; IPF, idiopathic pulmonary fibrosis; HCV, hepatitis c virus; BPD, bronchopulmonary dysplasia; ECM, extracellular matrix; ACE, angiotensin converting enzyme; ACE-2, angiotensin converting enzyme 2; Ang I, angiotensin I; Ang II, angiotensin II; Ang 1-7, angiotensin 1-7; AT1, angiotensin II receptor 1; AT2, ...

http://jra.sagepub.com/content/10/1/15 The online version of this article can be found at: DOI: 10.1177/1470320309102304 2009 10: 15 Journal of Renin-Angiotensin-Aldosterone System Edilamar M. Oliveira, Maurício S. Sasaki, Marcela Cerêncio, Valério G. Baraúna and José E. Krieger independent of circulating renin: a pharmacological study Local renin-angiotensin system regulates left ventricular h...

The renin-angiotensin system is a far more complex enzymatic cascade than realized previously. Mounting evidence suggests sex-specific differences in the regulation of the renin-angiotensin system and arterial pressure. We examined the hemodynamic responses, angiotensin II receptor subtypes, and angiotensin-converting enzyme 2 gene expression levels after graded doses of angiotensin II in males...

The pancreas is a relative newcomer to the stable of tissues with an intrinsic angiotensin-generating system. The involvement of this system in pancreatic activity will be dependent on the angiotensin-generating paths present in the pancreas and their precise cellular location. Thus far, renin, angiotensin-converting enzyme (ACE), angiotensin II and AT1 and AT2 receptors have been found. These ...

Dietary salt intake is a major determinant of the activation state of renin-angiotensin-aldosterone system. Given the important role of the renin-angiotensin-aldosterone system in plaque accumulation, we investigated its role in the development of atherogenesis associated with sodium intake in apolipoprotein E knockout mice. Six-weeks of a low-salt diet (containing 0.03% sodium) resulted in a 4...