Cryptorchidism in horses is the most common congenital malformation, caused by a failure descent of testicles from abdominal cavity into scrotum. As result, there partial or complete loss reproductive potential although production and secretion steroid sex hormones anti-Mueller hormone, as well behavioral characteristics stallion, are maintained. The exact location undescended testis establishe...

Large amounts of citric acid are present in certain secondary sexual organs of the adult male rat, notably the ventral prostate gland. The elegant investigations of Mann and his collaborators (l-3) have established that citrate accumulation in this tissue is clearly controlled by androgenic hormones, a conclusion which is particularly well illustrated by the finding of high concentrations of ci...

  The Kor River (Fars province) was divided into three parts and water and fish specimens were collected monthly and the concentrations of four heavy metals were determined using the Induction Coupled Plasma Method. As middle sampling zone was the main entrance and discharges of industries into the River, the concentrations of heavy metals in tissue of fish from this zone were significantly hig...

OBJECTIVE The relationship between musculoskeletal injuries and anabolic-androgenic steroids is not well understood. The purpose of our study was to investigate the association between self-reported anabolic-androgenic steroids use and the prevalence of musculoskeletal injuries in a unique group of retired professional football players. DESIGN A general health questionnaire was completed by 2...

BACKGROUND The androgen comprises a group of hormones that play roles in male reproductive activity as well as personal characteristics. OBJECTIVE We investigated the androgenic activity of various herbal medicines in human prostate cancer 22Rv1 cells. MATERIALS AND METHODS Herbal extracts of Trichosanthes kirilowii (TK), Asarum sieboldii (AS), Sanguisorba officinalis (SO), and Xanthium str...

background: nandrolone decanoate (nd) is an anabolic androgenic steroid (aas) which influences the ovarian structure and function. we assessed the effects of nd on the ovarian volume, number of primordial follicles, and level of hormones and also evaluated the modulatory effects of gonadotropins on the histopathological changes imposed by the administration of nd. methods: six groups of sprague...

Urinary concentrations of metabolites of the anti-androgenic xenobiotic di-(2-ethylhexyl) phthalate (DEHP) were previously shown to be weakly associated with serum levels of several hormones in 2 disparate US populations: partners of pregnant women participating in the Study for Future Families and partners in infertile couples from Massachusetts General Hospital infertility clinic. The ob...

The evidence of the literature indicates that the adrenal cortex produces a variety of hormones, some of which, like desoxycorticosterone, act predominantly to maintain a normal water and electrolyte balance (1), while others, like corticosterone, are effective chiefly through preventing hypoglycemia, either by facilitating the formation of sugar from protein (gluconeogenesis) (2) or by inhibit...

Background: Nandrolone decanoate (ND) is an anabolic androgenic steroid (AAS) which influences the ovarian structure and function. We assessed the effects of ND on the ovarian volume, number of primordial follicles, and level of hormones and also evaluated the modulatory effects of gonadotropins on the histopathological changes imposed by the administration of ND. Methods: Six groups of Sprague...

Despite the identification of numerous autism susceptibility genes, the pathobiology of autism remains unknown. The present "case-control" study takes a global approach to understanding the molecular basis of autism spectrum disorders based upon large-scale gene expression profiling. DNA microarray analyses were conducted on lymphoblastoid cell lines from over 20 sib pairs in which one sibling ...