The causal link between disparate tropomyosin (Tm) functions and the structural instability in Tm is unknown. To test the hypothesis that the structural instability in the central region of Tm modulates the function of the overlapping ends of contiguous Tm dimers, we used transgenic mice (Tm(DM)) that expressed a mutant α-Tm in the heart; S229E and H276N substitutions induce structural instabil...

The nature of the physicochemical interaction in Tm-As-S and Tm-As-Se systems was studied along various cross sections by methods Differential Thermal (DTA), X-Ray Diffraction (XRD) Microstructural (MSA) Analyzes, measuring their micro-hardness determining electrophysical properties. investigation alloys system started studying properties initial components cooling modes 7–10deg/min. After esta...

Effects of trimebutine maleate (TM-906) on the spontaneous motility of the gastrointestinal tracts were investigated in anesthetized dogs by means of force transducers. TM-906, administrated intravenously or intraduodenally, produced an inhibition followed by a potentiation of the spontaneous motility in the stomach, and caused a potentiation of the spontaneous motility in the duodenum, jejunum...

successful organizations take action to ensure that they have the human resources to meet their current and future business needs. organizations require much greater flexibility to account for individual needs than in the past and have to find new ways to manage resulting challenges. talent management (tm) will play a critical role in this context to help businesses succeed. talent management i...

Background: Exosomes in synovial fluid (SF) has a close relationship with the pathogenesis of rheumatiod arthritis. As complex biological fluid, SF presents challenges for exosomes isolation using standard methods, such as Exoquick TM kit and ultracentrifugation. Objectives: The study aims to compared quality separated by (TM), kit+Exoquick TC (TM-TC), ultracentrifugation (UC) TM-TC+UC(TM-TC-UC...

Thrombomodulin (TM), a membrane proteoglycan on endothelial cells, binds thrombin in a 1:1 complex, accelerates the protein C activation by thrombin, promotes the thrombin inactivation by antithrombin III and inhibits the procoagulant properties of thrombin. The inactivation of single-chain urokinase-type plasminogen activator (scu-PA) by thrombin is accelerated about 70-fold by TM [De Munk, Gr...

Empirical models are important tools for relating field-measured biophysical variables to remotely sensed data. Regression analysis has been a popular empirical method of linking these two types of data to estimate variables such as biomass, percent vegetation canopy cover, and bare soil. This study was conducted in a semi-arid rangeland ecosystem of Qazvin province, Iran. This paper presents t...

Let $M$ be an orientable hypersurface in the Euclidean space $R^{2n}$ with induced metric $g$ and $TM$ be its tangent bundle. It is known that the tangent bundle $TM$ has induced metric $overline{g}$ as submanifold of the Euclidean space $R^{4n}$ which is not a natural metric in the sense that the submersion $pi :(TM,overline{g})rightarrow (M,g)$ is not the Riemannian submersion. In this paper...