OBJECTIVES To evaluate the frequency of and predictive factors for nevirapine-based highly active antiretroviral therapy (HAART) discontinuation. METHODS All patients receiving nevirapine as a component of HAART at our centre were retrospectively evaluated for efficacy and tolerability. Logistic regression was used to evaluate the influence of baseline characteristics on the outcome and Kapla...

many efforts have been made to model the the hot deformation (dynamic recrystallization) flow curves of different materials. phenomenological constitutive models, physical-based constitutive models and artificial neural network (ann) models are the main methods used for this purpose. however, there is no report on the modeling of warm deformation (dynamic spheroidization) flow curves of any kin...

various scaling methods such as relative viscosity, peclet and reynolds scaling were used to find the best scaling law. scaling and modeling of the flow curves of various model emulsions consist of tragacanth gum (tg) (0.5, 1 % wt), oleic acid (5, 10% v/v) and wpi (2, 4 % wt) were investigated and the best models were selected. as these emulsions are non-newtonian, they do not obey the usual, si...

In this study a simulation-optimization model is developed for deriving operation rule-curves in drought ‎periods. To each reservoir, two rule-curves with adjustable monthly levels are introduced dividing the ‎reservoir capacity into three zones between the normal water level and minimum operation level. To each ‎zone of a reservoir and for each month of the year a hedging coefficient is introd...

‎In the present study‎, ‎we consider a regular curve in Galilean‎ ‎$4$-space $mathbb{G}_{4}$ whose position vector is written as a‎ ‎linear combination of its Frenet vectors‎. ‎We characterize such‎ ‎curves in terms of their curvature functions‎. ‎Further‎, ‎we obtain‎ ‎some results of rectifying‎, ‎constant ratio‎, ‎$T$-constant and‎ ‎$N$-constant curves in $mathbb{G}_{4}$‎.

in this research, softening and ratcheting behaviors of ck20 alloy steel cylindrical shells were studied under displacement-control and force-control cyclic axial loading and the behavior of hysteresis curves of specimens was also investigated. experimental tests were performed by a servo-hydraulic instron 8802 machine. the mechanical properties of specimens were determined according to astm e8...

The accurate medical diagnostic of a disease condition is fundamental for a correct medical decision. Disease screening programs are based, in general, in diagnostic tests which provide a binary response: a subject is classified as positive, if the test result is above a given threshold, and negative, otherwise. Therefore, false positive and false negative classifications can be generated. The ...

Now a day centrifugal pumps are vital components of industries. Certainly, one of the most important specifications of centrifugal pumps are the performance curves. In the present work, performance curves of a centrifugal pumps are obtained by Computational fluid dynamics (CFD) and as an outcome, CFD results compare by practical curves. At the first step impeller and volute are designed with tw...