The standard view of modern human infectious diseases is that many of them arose during the Neolithic when animals were first domesticated, or afterwards. Here we review recent genetic and molecular clock estimates that point to a much older Paleolithic origin (2.5 million years ago to 10,000 years ago) of some of these diseases. During part of this ancient period our early human ancestors were...

In the modern medical era it has been known as well that physical activity and exercise are important factors to prevent from different chronic diseases. Scientifically, there are numerous evidence based studies about protective role of exercise against chronic diseases such as cardio- respiratory diseases, diabetes, and hyperlipidemia etc, which have been completely explained. Historically, an...

leprosy is an ancient disease, known from south asia since at least 2000 bce. while there is no physical evidence of this disease in the region before about 50 ce, five different words are translated as “leprosy” in mesopotamian texts and some of them occur frequently. based on the texts, one word (garāṣu) is rarely used and there is evidence that the other four words relate to diseases that we...

Dental diseases have detrimental effects on the functionality and quality of life of individuals. In addition, a strong relationship has been established between various oral and systemic diseases. In fact, the prevention and treatment of dental caries and periodontal disease have been shown to reduce the risk of diabetes and heart disease significantly. This goes beyond the role of oral health...

Mulberry is a fast growing woody perennial plant belonging to the family Moraceae. These plants gained attention since time immemorial due to its pharmacological and economic value. Use of mulberry leaves in sericulture has been reported in the ancient Chinese literature. Medicinal properties of this plant have been depicted in the ancient literature of Ayurveda. Some of the ayurvedic preparati...

This socio-sexual review of Ancient Egyptian society aims to increase awareness that the prevalence of sexually transmitted diseases (STDs) is largely determined by the way a society is structured and how that structure functions. The prevalence of STDs in Ancient Egypt has been found to be low. This state of affairs was maintained for centuries. Although the structure of their society was rigi...

Our understanding of the evolution of domestication has changed radically in the past 10 years, from a relatively simplistic rapid origin scenario to a protracted complex process in which plants adapted to the human environment. The adaptation of plants continued as the human environment changed with the expansion of agriculture from its centres of origin. Using archaeogenomics and computationa...

The medieval Norsemen or Vikings had an important biological and cultural impact on many parts of Europe through raids, colonization and trade, from about AD 793 to 1066. To help understand the genetic affinities of the ancient Norsemen, and their genetic contribution to the gene pool of other Europeans, we analysed DNA markers in Late Iron Age skeletal remains from Norway. DNA was extracted fr...

Recently, the study of ancient DNA (aDNA) has been greatly enhanced by the development of second-generation DNA sequencing technologies and targeted enrichment strategies. These developments have allowed the recovery of several complete ancient genomes, a result that would have been considered virtually impossible only a decade ago. Prior to these developments, aDNA research was largely focused...

Phylogenetic analyses of ancient DNA data can provide a timeline for evolutionary change even in the absence of fossils. The power to infer the evolutionary rate is, however, highly dependent on the number and age of samples, the information content of the sequence data and the demographic history of the sampled population. In this issue of Molecular Ecology, Sheng et al. (2014) analysed mitoch...