conclusions treatment strategies in acquired hemophilia are based on two major objectives. during the acute stage, effective control of bleeding is critical. the ultimate therapeutic goal during the subacute phase is the elimination of the inhibitors targeting factor viii. here, we present this case and will review current literature regarding therapeutic approaches to this rare condition in th...

background: genistein is a soya isoflavone, which is found naturally in legumes, such as soybeans and chickpeas. radiation–induced free radicals in turn impair the antioxidative defense mechanism, leading to an increased membrane lipid peroxidation that results in damage of the membrane bound enzyme and may lead to damage or death of cell. hence, the lipid peroxidation is a good biomarker of da...

the review of literature shows that a strong relationship exists between the symptoms of otolaryngologic diseases and gastroesophageal reflux disease (gerd). it is commonly observed that an extended physical examination is needed to determine the occurrence of gerd. this non-randomized,prospective quasi-experimental study was performed to clinically verify the relationship between otolaryngolog...

aromatase inhibitors (ais) as effective candidates have been used in the treatment of hormone-dependent breast cancer. in this study, we have proposed 300 structures as potential ais and filtered them by lipinski’s rule of five using druglito software. subsequently, they were subjected to docking simulation studies to select the top 20 compounds based on their gibbs free energy changes and also...

acetylcholinesterase (ache) is the main enzyme for the breakdown of acetylcholine. nowadays, usage of the inhibitors of this enzyme is one of the most important types of treatment of mild to moderate neurodegenerative diseases such as alzheimer’s disease. herbal medicines can be a new source of inhibitors of this enzyme. in this study we examined around 100 different plants to evaluate their in...

angioedema is characterized by recurrent, circumscribed, solitary or multiple subcutaneous and mucosal swelling, involving the extremities, face, larynx, bowel wall. angioedema is due to hereditary or acquired varieties of c1 esterase inhibitor (c1inh) deficiency. a case of atypical acquired angioedema in a 49-year old man, responding favourably to cinnarizine and alcohol abstinence, is present...

Background: Factor VIII administration to hemophilia A patients results in an immune response (inhibitor formation) which significantly complicates the therapy. The present study was performed to determine the prevalence of inhibitor development in hemophilia A patients receiving recombinant factor VIII therapy. Materials and Methods: This was an observational descriptive study. Clotting fac...

This study set out to examine the cystoseira gibraltarica extract (CG) as an environmentally sustainable corrosion inhibitor for carbon steel in 1.0 M HCl medium. The corrosion inhibiting effect has been studied by conventional methods such as gravimetric (weight loss) and electrochemical (EIS and PDP) methods. All the methods used in this study confirm that cystoseira gibraltarica extract has ...

Treated sea water is the most significant source of water and surfactant floods. The various chemicals employed in treatment plants should be compatible with surfactant systems. Based on surface tension experiments, the activity of these chemicals is examined over a wide range of concentrations in different solutions, including distillated water, sea water by using three types of surfactant mix...

in this work, electrochemical methods such as tafel polarization and electrochemical impedance spectroscopy (eis) were used to study the inhibition efficiency of nettle leaves hydroalcoholic extract as a green corrosion inhibitor of api 5l carbon steel in 0.5 m h2so4 solution. the results showed that the inhibition efficiency was increased with increasing the concentration of the extract and th...