Acute Megakaryoblastic Leukemia (AMKL) is a rare subtype of acute myeloid leukemia classified as AML M7 by the French–American–British (FAB) Leukemia Cooperative Study Group. We reviewed the records of children aged less than 18 years with AMKL during the period from January 2003 to December 2010. The diagnosis of AMKL was established on the basis of the FAB criteria and confirmed by immunophen...

Two strains of psychrotolerant bacteria, designated M7(T) and M5, isolated from Antarctic coastal marine environments were studied to determine their taxonomic position. The organisms comprised Gram-negative, rod-shaped, facultatively anaerobic cells that were motile by means of single polar flagella. Neither of the bacterial isolates had a requirement for Na(+). These two psychrotolerant strai...

background: the human aml1 gene, located on chromosome 21, can be fused to the aml1- eight-twenty-one (eto) oncoprotein on chromosome eight, resulting in a t(8;21)(q22;q22) translocation. acute myeloid leukemia (aml) associated with this translocation is considered a distinct aml with a favorable prognosis. due to the various incidences of the translocation, which is associated with geographic ...

Older age is a poor prognosis factor in acute myeloid leukemia (AML). This double-blind trial was designed to test the hypothesis that granulocyte colony-stimulating factor (G-CSF) used as supportive care could improve the treatment of elderly AML patients. Two hundred thirty-four patients 55 or more years of age with a morphologic diagnosis of de novo or secondary AML, French-American-British ...

Older age is a poor prognosis factor in acute myeloid leukemia (AML). This double-blind trial was designed to test the hypothesis that granulocyte colony-stimulating factor (G-CSF) used as supportive care could improve the treatment of elderly AML patients. Two hundred thirty-four patients 55 or more years of age with a morphologic diagnosis of de novo or secondary AML, French-American-British ...

Abstract Acute myeloid leukemia (AML) M4, M5, and M7 are subtypes of derived from cell derivatives that influences the results identification AMLs, which includes myeloblast, monoblast, megakaryoblast. Furthermore, they divided into more specific types, including myeloblasts, promyelocytes, monoblasts, promonocytes, monocytes, megakaryoblasts, must be clearly identified in order to further calc...

A recent paper by Dastugue et al1 reported the cytogenetic profile of 53 patients with acute megakaryoblastic leukemia (FAB-M7). The authors studied 30 children and 23 adults evaluated by the Groupe Français de Cytogénétique Hématologique, and identified 9 different groups based on their conventional cytogenetic analysis. These groups reflect, in part, the known association of M7 leukemia with ...