A thermostable nuclease homologue (NucM) in an animal-associated divergent clade of Staphylococcus aureus in sub-Saharan Africa has a highly divergent nucleotide sequence compared to those of the classical nuc1 and nuc2 genes of S. aureus. Its deduced amino acid sequences, tertiary structures, and nuclease activities, however, are similar.

1. In the present study we have examined the sensitivity of A and ASC amino-acid-carrier activities in rat liver plasmamembrane vesicles to the thiol-group modifying reagents N-ethylmaleimide (NEM) and iodoacetamide (IA). To this end, the different Na+-dependent entities involved in alanine transport were assessed. 2. NEM inactivated Na+-dependent alanine transport as a result of the inhibition...

background: infectious bronchitis is a highly contagious disease which may cause poor weight gain and low feed efficiency in infected chickens. there are a large number of reported serotypes/genotypes, which makes the control of the disease more difficult through vaccination. however, there are only a few amino acid differences in the s1 protein of vaccine and wild type strains which are respon...

the mucus layer plays an important role as an intermediate for the protection of the gut against acidic chyme, digestive enzymes, and pathogens; in addition, it acts as a lubricant and facilitator of nutrient transportation. phytogenic compounds seem to promote intestinal mucus production. objectives: the current study was conducted to investigate the effects of low and high levels of energy an...

Although macromolecular synthesis inhibitors have been demonstrated to prevent neuronal apoptosis in a number of paradigms, their mechanisms of protection remains unclear. Recently, we found that neuronal death resulting from cystine deprivation, glutathione loss, and oxidative stress is apoptotic and is prevented by inhibitors of macromolecular synthesis. We now report that protection is assoc...

The widely used pseudorabies virus (PRV) Bartha-K61 vaccine has played a key role in the eradication of PRV. Since late 2011, however, a disease characterized by neurologic symptoms and a high number of deaths among newborn piglets has occurred among Bartha-K61-vaccinated pigs on many farms in China. Clinical samples from pigs on 15 farms in 6 provinces were examined. The PRV gE gene was detect...

The mucus layer plays an important role as an intermediate for the protection of the gut against acidic chyme, digestive enzymes, and pathogens; in addition, it acts as a lubricant and facilitator of nutrient transportation. Phytogenic compounds seem to promote intestinal mucus production. OBJECTIVES: The current study was conducted to investigate the effects of low and high levels of energy an...