A copolymer of dodecyl methacrylate/styrene (DMA/St) containing the amidine functionality was synthesized and characterized. The one-step solution copolymerization process was carried out using a mixed solvent, high temperature, and a functional azo initiator, 2,2 -azobis[N,N -dimethylene isobutyramidine]. Copolymers with different compositions (DMA/St 10/1 to 1/2), molecular weight (Mn 2000–90...

The title compound, C(19)H(13)N(5)O(3), can be obtained from the corresponding α-amido-α-amino-nitrone in a reaction with biphenyl-2,2'-diamine. The amido-amidine core has distinctive geometrical parameters including: an outstandingly long Csp(2)-Csp(2) single bond of 1.5276 (13) Å and an amidine N-C-N angle of 130.55 (9)°. Intra-molecular N-H⋯O, N-H⋯N and C-H⋯O hydrogen bonds occur. In the cry...

The coordination between N-p-methylbenzyl-d-galactonoamidine, a putative transition state analogue of the hydrolyis of glycosidic bonds, and symmetric and chiral binuclear copper(ii) complexes was characterized by spectroscopic titration, isothermal titration calorimetry, circular dichroism spectroscopy, and DFT calculations to elucidate the binding sites in the carbohydrate upon coordination t...

The amidine complexes cis-[L(2)PtNH==C(R){1-MeCy(-2H)}]NO(3) (R = Me, 1a; Ph, 1b, Me(3)C, 1c; Ph(2)(H)C, 1d) and cis-[L(2)PtNH==C(R){9-MeAd(-2H)}]NO(3) (R = Me, 2a; Ph, 2b; Me(3)C, 2c; Ph(2)(H)C, 2d), are formed when cis-[L(2)Pt(μ-OH)](2)(NO(3))(2) (L = PPh(3)) reacts with 1-methylcytosine (1-MeCy) and 9-methyladenine (9-MeAd) in solution of MeCN, PhCN, Me(3)CCN and Ph(2)(H)CCN. Reaction of 1a,...

Bis(chlorotetrylene)s of Si, Ge, and Sn have been synthetically realized starting from the backbone-bridged bis(amidine) 1. Double deprotonation 1 subsequent reaction with trichlorosilane affords bis(dichorosilane) 2, which is converted to respective bis(chlorosilylene) 3 by dehydrochlorination using lithium bis(trimethylsilyl)amide. The related bis(chlorogermylene) 4 bis(chlorostannylene) 5 ar...

In contrast to amidines bearing ionizable alpha-CH bonds, which react with nitric oxide (NO) to add diazeniumdiolate groups at their alpha-carbons, benzamidine forms an N-bound diazeniumdiolate that can be further derivatized at the other amidine nitrogen and/or the terminal oxygen to form caged NO compounds as potential NO prodrugs.

Cobyric acid (1) is a member of the corrin class of hydroporphyrins,1 which incorporate a vinylogous amidine chromophore within a tetrapyrroline skeleton. Members of this class have been the subject of extensive studies, not only because of their biological importance but also due to their intriguing biosynthetic pathway.2 Recently, this area has seen a resurgence of interest from synthetic che...

A new heterometallic electroactive compound having the ferrocenyl moiety attached to the platinum atom through an amidine functionality has been prepared via Pt(II)-mediated nucleophilic addition of β-aminoethylferrocene to a benzonitrile ligand. This neutral receptor shows remarkable electrochemical anion-sensing redox response to H(2)PO(4)(-).

A novel benzopyrano[4,3-d]pyrimidine scaffold was generated via a three-component one-pot reaction from iodochromone, alkyne, and an amidine through a Sonogashira coupling, condensation, and cycloaddition. This combinatorial synthetic approach provides an efficient, easy construction of a diversified heterocyclic compounds library.