Malignant melanoma is known for its wide range of histologic patterns and its ability to mimic other malignant tumors. Malignant melanoma is generated in the skin and sinus paranasalis by a malignant tumor of melanocytic origin. Malignant melanoma is usually quickly diagnosed by the presence of melanin granules. On the other hand, amelanotic melanoma is without melanin granules and is often dif...

The case of an 89-year-old man who was referred for a painless decrease of vision in his right eye (RE) is reported. Fundus examination of the RE showed an elevated amelanotic lesion located in the posterior pole with an adjacent focal round pigmented lesion. There was also a more peripheral amelanotic lesion extending from 6 to 9 o'clock clockwise inferotemporally. Uveitis workup and imaging s...

DERMOSCOPIC APPEARANCE The dermoscopic analysis (Fig 2) revealed peripheral dotted vessels, linear irregular vessels, milky red areas, and white streaks, suggestive of melanoma. However, there were no structures or vascular patterns found in cutaneous epitheliomas, such as leaf-like areas, blue-gray ovoid nests, or arborizing or glomerular vessels. It is noteworthy that no brown, black, gray, o...

The subject of the study was the influence of two lines of transplantable melanomas on the secretion of cytokines (IL-6, TNF-alpha, OSM) and total proteins by hamster peritoneal macrophages. The results showed a statistically significant increase of total protein content and decrease of cytokine content in the supernatants of 24 h cultured macrophages from melanoma-bearing animals in comparison...

PATIENT Male, 55 FINAL DIAGNOSIS: Melanoma Symptoms: Worsening constipation • tenesmus • weight loss MEDICATION - Clinical Procedure: Chemoradiation therapy Specialty: Oncology. OBJECTIVE Challenging differential diagnosis. BACKGROUND Malignant melanoma is usually readily diagnosed by the presence of melanin granules. Although amelanotic melanoma contains a few melanin granules, it is oft...

To evaluate the magnetic resonance (MR) imaging characteristics of primary malignant melanoma of the sinonasal cavity, T1- and T2-weighted MR images of 12 patients with primary sinonasal melanoma were retrospectively reviewed. Gadolinium-enhanced imaging was performed in seven cases. The MR images were compared with histopathologic results. There were seven melanotic melanomas and five amelanot...

BACKGROUND Lentigo malignant melanoma is a melanoma subtype of chronic sun-damaged skin in elderly Caucasians. Amelanotic variants of lentigo malignant are extremely rare. CASE PRESENTATION This is a case report of an 80-year-old male patient who presented with a non-pigmented exophytic tumour of his bald head. After complete surgical excision under the suspicion of squamous cell carcinoma, t...