Historically, mortality after Amanita mushroom ingestion has ranged from 50% to 90%. Prompt diagnosis is imperative, and aggressive therapeutic measures must be instituted quickly to improve the outcome. We report successful treatment of two cases of A. virosa poisoning by use of combined therapies, including thioctic acid and hemoperfusion.

By the addition of phalloidin, an oligopeptide of Amanita phalloides, to platelet-rich plasma, an increase of its transparency could be observed. The rate of increase of transparency was slow but the maximal intensity corresponded to that of ADP aggregation. Morphologically, many microfilaments were formed in the cytoplasm. But the figures were different from those in platelets in ADP aggregation.