Brain is the most complex and master organ of the human body. Quantitative analysis of anatomical brain tissues such as GM and WM is important for the clinical diagnosis and therapy of neurological diseases. Brain imaging is a widely used method by the doctors and clinicians for the representation of human brain. Magnetic Resonance Imaging (MRI) is a recently emerged method for brain imaging. A...

important degenerative disease of brain.1,2 Several theories have been raised for Alzheimer disease including genetic deficiencies, slowly-progressive viral diseases, neutrophilic factors deficiencies, amyloid, free radicals, mitochondrial deficiencies and glutamate poisoning.3,4 One important phenomenon in these diseases is changes observed in copper and iron homeostasis.5,6 Since iron serum l...

In previous studies the carboxyl-terminus of microtubule-associated protein 1S was shown to interact with the N-methyl-D-aspartate receptor subunit NR3A (Eriksson et. al.) 1. In this study, interactions between three truncations of the microtubule-associated proteins 1B and one truncation of the microtubule-associated protein 1S carboxyl-terminus and the N-methyl-D-aspartate receptor subunits N...

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Alzheimers disease is the most common form of dementia in adults aged 65 or older. While many neuro-imaging based biomarkers have been proposed over the years for detection of AD, these have mostly been hand-crafted and utilized domain-specific clinical knowledge. In this project, we are interested in automatically discovering such biomarkers (hidden cues) by using deep learning methods to clas...