among the drug delivery and targeting (ddt) routes, lung alveolar epithelium has been given enormous attentions in terms of the delivery of a wide range of macromolecules such as gene- or protein-based nanopharmaceuticals. however, little is known about cellular modulation of lung transport characteristics by endogenous and/or exogenous agents. thus, in the current study, impact of dexamethason...

it was known that il-1β-induced rapid expression of mir-146a, which regulated the secretion of inflammatory chemokines in human a549 alveolar epithelial cells. however, little is known about the level of primary mir-146a and the downstream biogenesis of mir-146a in a549 cells. we examined the levels of primary mir-146a and mature mir-146a in a549 cells following treatment with pharmacological i...

excessive alveolar bone resorption is commonly found when teeth are extracted. this is a problem in anterior part of mouth because it will result in an unaesthetic pontic on a narrow hollowed out alveolar ridge. yet, another problem is gingival recession and root exposure in adjacent teeth which represent a therapeutic problem to the clinician. use of acellular dermal matrix graft is an appropr...

background: it has been shown that inhalation of carbonaceous particulate matter may impair lung function in children. objective: using the carbon content of airway macrophages as a marker of individual exposure to particulate matter derived from fossil fuel, we sought direct evidence for this association. methods: 300 children from puffed rice industrial areas and 300 children from population ...

alveolar ridge resorption has long been considered an unavoidable consequence of tooth extraction. while the extent and pattern of resorption is variable among individuals, there is a progressive loss of ridge contour as a result of physiologic bone remodeling. even today, with best modalities of tooth preservation, there is a group of elderly individuals who do not benefit from modern preventiv...

Phagocytosis and killing by alveolar macrophages from humans, rabbits, rats, and hamsters, were compared in vitro. In the absence of serum opsonins, human alveolar macrophages could phagocytize Staphylococcus aureus Cowan I (protein A positive), but not S. aureus EMS (protein A negative) or Pseudomonas aeruginosa MN. In contrast, rabbit, rat, and hamster alveolar macrophages did not phagocytize...

This study is to use cone beam computed tomography (CBCT) to acquire accurate radiographic images for alveolar bone in lower incisors and the change after presurgical orthodontic treatment. Seventeen patients with skeletal Class III malocclusion, ten normal occlusion subjects, and fifteen patients treated with orthodontic treatment and orthognathic surgery were included. CBCT images were obtain...