This work investigates Application Lifecycle Management (ALM) and elaborates a methodology for building an ALM platform for organizations dealing with manufacturing of software products. The meaning of platform is defined and available ALM platforms on the market are analyzed as a part of the methodology execution. Emphasis is put on basic principles coming from PLM – Product Lifecycle Manageme...

This paper reports an experiment conducted to examine the effects of changing the form of strategic interactions (Bertrand or Cournot), and changing underlying information conditions on the usefulness of the ‘ALM,’ a merger simulation device used by the U.S. Department of Justice. The experiment consists of twenty 60-period quadropolies. After period 40 a merger is induced. Behaviorally, Courno...

In this paper, we present and evaluate three applicationlayer multicast (ALM) protocols, namely Narada [3–5], NICE [1,2], and an ALM protocol implemented using the Internet Indirection Infrastructure (i3 ) [11]. We evaluate these three ALM protocols according to the quality of their data delivery paths, their robustness to changing membership, changing network characteristics, and failures, and...

As a way of implementing multicast delivery, applicationlevel multicast (ALM) is known for its various advantages including high flexibility and easy deployment. However, one of its key limitations in achieving reliability and quality-of-service (QoS) for streaming services is the hierarchical error propagation caused by its tree structure. As a solution to this error propagation problem, we pr...

In this paper, we present a thorough and realistic analysis of audio conferencing over application-level multicast (ALM). Through flexibility and ease-of-deployment, ALM is a compelling alternative group-communication technique to IP Multicast — which has yet to see wide-scale deployment in the Internet. However, proposed ALM techniques suffer from inherent latency inefficiencies, which we show...

Limb regeneration is a representative phenomenon of organ regeneration in urodele amphibians, such as an axolotl. An amputated limb starts regenerating from a remaining stump (proximal) to lost finger tips (distal). In the present case, proximal-distal (PD) reorganization takes place in a regenerating tissue, called a blastema. It has been a mystery how an induced blastema recognizes its positi...

A variety of issues, both technical and commercial, has hampered the widespread deployment of IP multicast in the global Internet. Application Level Multicast (ALM) approaches using the overlay network have been recently proposed as a viable alternative to IP multicast. In this paper, we proposed a DNS-aided ALM which builts overlay network with the help of the existing Domain Name Service (DNS...

B-lineage acute lymphoblastic leukemia (ALL) may express CD52 and CD20. Alemtuzumab (ALM) and rituximab (RTX) are therapeutic antibodies directed against CD52 and CD20, respectively, but showed limited activity against ALL in clinical trials. The mechanisms for the impaired responses remained unclear. We studied expression of CD52 and CD20 on ALL cells and found that most cases coexpressed CD52...

Sound ALM practices ensure the stability and liquidity of banks, thus enhancing the profitability. ALM is a mechanism to address the risk faced by banks due to mismatch in assets and liabilities. In the context of India, banking industry is closely monitored and supervised by Reserve Bank of India (RBI). As a part of many norms to ensure the sound banking system, RBI also has come out with the ...

We have developed an anesthetized microswine model of hypoxemic hypothermia and rewarming for testing prophylaxes and treatments. The respiratory stimulant almitrine bismesylate (ALM) was considered as a potential field expedient therapy for hypoxemic hypothermia. Preliminary experiments demonstrated that five consecutive 100 micrograms.kg-1 ALM intravenous (i.v.) doses given to normothermic mi...