Many drugs are available to treat allergic condition. This review focused on why antihistaminics best choice for treatment of disorder especially rhinitis (AR). AR is a chronic inflammatory disease. can be detected by its characteristics nasal congestion, itching, sneezing, rhinorrhoea, pruritis, redness, tearing and itching eyes. very common increases day after day. Allergic not lethal but int...

Background Allergy is a common disorder in the western world with a prevalence of 15% to 20%. The combination of ocular symptoms in patients with allergic rhinitis occurs frequently. Nasal mucus for the nasal epithelium and tear fluid for the eye are the first defence barrier against various pathogens including aeroallergens. Little is known about the nasal mucus and particularly about the tear...

Allergic fungal sinusitis (AFS) is a benign, extramucosal, noninvasive fungal sinus disease representing an allergic/hypersensitivity response to extramucosal fungal pathogens in the sinus [1]. It occurs mainly in immunocompetent patients, in contrast to invasive fungal diseases that usually involve an immunocompromised host. The incidence of AFS in patients affected by chronic rhinosinusitis a...

Background Allergic rhinitis (AR) is a complex inflammatory disorder where antigen presenting cells (APCs) are believed to activate allergen-specific CD4+ T cells at the site of allergen exposure. By sorting cells from the nasal mucosa in an experimental model of AR we have found, at the transcriptome level, that the total population of CD45+ HLA-DR+ cells showed signs of activation concomitant...

The ingestion of dietary gluten sometimes may trigger allergic, autoimmune or nonallergic and nonautoimmune response. The typical gluten‑related allergic disorder is the wheat allergy (WA). Celiac disease (CD) is a well‑known gluten‑related autoimmune condition. The clinical expression of a gluten‑related nonallergic and nonautoimmune response is nonceliac gluten sensitivity (NCGS), an emerging...

BACKGROUND Allergic rhinitis is a complex polygenic disorder of the upper respiratory tract. Given that proinflammatory cytokines such as tumor necrosis factor (TNF) and interleukin (IL) 1 seem to play a role in the development of allergic rhinitis, we evaluated the associations between various single-nucleotide polymorphisms (SNPs) of the TNF and IL1 genes in a case-control study. METHODS Th...

BACKGROUND Recently, extensive research has established that epidemiologic and therapeutic links exist between allergic rhinitis and asthma. The objective of this study was to clarify this association in Iraq. METHODS The data included in this study were collected from five surveys for asthma and allergic rhinitis that were performed during the period from September 2000 to July 2008. These s...

Atopic dermatitis (AD) is a condition frequently encountered in medical practices across the country. More than 60% of children with AD are at risk to develop allergic rhinitis or asthma (the atopic march). Patients with AD have a unique predisposition to colonization or infection by Staphylococcus aureus. Treatments for AD need to rapidly control symptoms of the disease, improve quality of lif...

We performed a MeSH term-based bibliometric analysis aiming to assess the publication trends of EAACI journals, namely Allergy, Pediatric Allergy and Immunology (PAI) (from 1990 to 2015) and Clinical and Translational Allergy (CTA) (from its inception in 2011 to 2015). We also aimed to discuss the impact of the creation of CTA in the publication topics of Allergy and PAI. We analysed a total of...

BACKGROUND Few longitudinal data exist on the incidence of asthma in young adults and on the overall mortality risk due to asthma. A 7-year follow-up prospective study was performed to assess the incidence of asthma and mortality from all causes in a cohort of young adults. METHODS The life status of a cohort of 6031 subjects, aged 20-44 years, who replied to a respiratory screening questionn...