نتایج جستجو برای: ali rafiee

تعداد نتایج: 9454  

Journal: :The Journal of clinical investigation 2013
Hong Zhang Patrick Neuhöfer Liang Song Björn Rabe Marina Lesina Magdalena U Kurkowski Matthias Treiber Thomas Wartmann Sara Regnér Henrik Thorlacius Dieter Saur Gregor Weirich Akihiko Yoshimura Walter Halangk Joseph P Mizgerd Roland M Schmid Stefan Rose-John Hana Algül

Acute lung injury (ALI) is an inflammatory disease with a high mortality rate. Although typically seen in individuals with sepsis, ALI is also a major complication in severe acute pancreatitis (SAP). The pathophysiology of SAP-associated ALI is poorly understood, but elevated serum levels of IL-6 is a reliable marker for disease severity. Here, we used a mouse model of acute pancreatitis-associ...

Journal: :Molecular biology of the cell 1993
Y Ohya H Qadota Y Anraku J R Pringle D Botstein

Geranylgeranyl transferase I (GGTase I), which modifies proteins containing the sequence Cys-Ali-Ali-Leu (Ali: aliphatic) at their C-termini, is indispensable for growth in the budding yeast Saccharomyces cerevisiae. We report here that GGTase I is no longer essential when Rho1p and Cdc42p are simultaneously overproduced. The lethality of a GGTase I deletion is most efficiently suppressed by pr...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده علوم 1391

دریاچه مهارلو یکی از دریاچه های شور ایران است که در استان فارس و در 23 کیلومتری جنوب شرقی شیراز قرار دارد و به دلیل فاصله کم آن از شهر شیراز و مجاورت آن با تعداد زیادی روستا و نیز به دلیل استفاده از نمک دریاچه در صنایع مختلف دارای اهمیت ویژه ای است. با بکارگیری فنون سنجش از دور چند طیفی می-توان درمدت زمانی کوتاه و با کمترین هزینه و نیروی کار به اطلاعات مفیدی در زمینه زمین شیمی دریاچه ها به ویژه...

Journal: :The Journal of clinical investigation 2006
Alexander Zarbock Kai Singbartl Klaus Ley

Acute lung injury (ALI) causes high mortality, but its molecular mechanisms are poorly understood. Acid aspiration is a frequent cause of ALI, leading to neutrophil sequestration, increased permeability, and deterioration of gas exchange. We investigated the role of platelet-neutrophil interactions in a murine model of acid-induced ALI. Acid aspiration induced P-selectin-dependent platelet-neut...

Journal: :Cell 2008
Yumiko Imai Keiji Kuba G. Greg Neely Rubina Yaghubian-Malhami Thomas Perkmann Geert van Loo Maria Ermolaeva Ruud Veldhuizen Y. H. Connie Leung Hongliang Wang Haolin Liu Yang Sun Manolis Pasparakis Manfred Kopf Christin Mech Sina Bavari J. S. Malik Peiris Arthur S. Slutsky Shizuo Akira Malin Hultqvist Rikard Holmdahl John Nicholls Chengyu Jiang Christoph J. Binder Josef M. Penninger

Multiple lung pathogens such as chemical agents, H5N1 avian flu, or SARS cause high lethality due to acute respiratory distress syndrome. Here we report that Toll-like receptor 4 (TLR4) mutant mice display natural resistance to acid-induced acute lung injury (ALI). We show that TLR4-TRIF-TRAF6 signaling is a key disease pathway that controls the severity of ALI. The oxidized phospholipid (OxPL)...

Journal: :IEEE Trans. Geoscience and Remote Sensing 2003
Shunlin Liang Hongliang Fang Monisha Kaul Tom G. Van Niel Tim R. McVicar Jay S. Pearlman Charles L. Walthall Craig S. T. Daughtry Karl Fred Huemmrich

The Advanced Land Imager (ALI) is a multispectral sensor onboard the National Aeronautics and Space Administration Earth Observing 1 (EO-1) satellite. It has similar spatial resolution to Landsat-7 Enhanced Thematic Mapper Plus (ETM+), with three additional spectral bands. We developed new algorithms for estimating both land surface broadband albedo and leaf area index (LAI) from ALI data. A re...

Journal: :Critical Care 2007
Simon J Finney Timothy W Evans

The incidence of acute lung injury (ALI) is influenced by nature of the underlying clinical condition. The frequency with which ALI is likely to be encountered by those practicing outside the intensive care unit (ICU) setting is largely unknown. Data from the paper under discussion indicates that ALI is seen relatively frequently in general wards and can be managed there until death or recovery...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2012
Yosaf F Zeyed Julie A Bastarache Michael A Matthay Lorraine B Ware

The rate of alveolar fluid clearance (AFC) is associated with mortality in clinical acute lung injury (ALI). Patients with ALI often develop circulatory shock, but how shock affects the rate of AFC is unknown. To determine the effect of circulatory shock on the rate of AFC in patients with ALI, the rate of net AFC was measured in 116 patients with ALI by serial sampling of pulmonary edema fluid...

2002
John-Paul Hosom

This paper presents a method for speaker-independent automatic phonetic alignment that is distinguished from standard HMM-based “forced alignment” in three respects: (1) specific acoustic-phonetic features are used, in addition to PLP features, by the phonetic classifier; (2) the units of classification consist of distinctive phonetic features instead of phonemes; and (3) observation probabilit...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2004
Russell P Bowler Beth Duda Edward D Chan Jan J Enghild Lorraine B Ware Michael A Matthay Mark W Duncan

Proteomics is the large-scale analysis of protein profiles. This approach has not yet been reported in the study of acute lung injury (ALI). This study details protein profiles in plasma and pulmonary edema fluid (EF) from 16 ALI patients and plasma and bronchoalveolar lavage fluid (BALF) from 12 normal subjects. More than 300 distinct protein spots were evident in the EF and BALF of both norma...

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