background and objectives: treatment of pseudomonas aeruginosa infections is greatly hampered by innate and acquired antibiotic resistance. the goal of this study was to compure the immunogenicity of conjugates of p. aeruginosa depolymerized alginate-diphtheria toxoid (d-algdt) and p. aeruginosa detoxified lipopolysaccharidediphtheria toxoid (d-lpsdt) in mouse model. materials and methods: algi...

The solution casting method was utilized to synthesize nanocomposite films of chitosan (Cs)/CuO, Cs/graphene oxide (GO), carboxymethyl cellulose (CMC)/TiO2, CMC/GO, sodium alginate (Na-Alg)/TiO2, and Na-Alg/GO owing their various applications. influence CuO, TiO2 GO concentration on the optical properties Cs, CMC Na-Alg studied by UV-Vis Spectroscopy. absorbance increased with increasing filler...

Strontium (Sr) is known to positively affect the mechanism of bone remodelling. Consequently, calcium phosphate bioceramics associated with alginate matrices containing strontium could improve bone regeneration due to gradual strontium release. This work aims to incorporate Sr on microspheres of alginate (ALG)/β-tricalcium phosphate (β-TCP) and evaluates the in vitro release of strontium ions i...

In this study, we describe the synthesis of zinc oxide nanoparticles (ZnO NPs) and evaluate impact alginate-based ZnO NPs (Alg–ZnO on microbiological activity, storage behavior, physico-chemical properties ‘Kiett’ mango fruit. The fruits were coated with alginate Alg–ZnO then stored at 13 °C; uncoated used as controls. synthesized characterized, confirming formation spherically shaped particles...

Inhibition of B. cinerea by alginate (Alg) / cajuput essential oil (Caj) at different concentration (0%, 0.25%, 0.5%, 0.75%) and the composite’s surface properties were investigated. Among samples, treated spore with Caj 0.75% showed lowest germination percentage germ tube length. The regarded antifungal action was confirmed observing changes membrane integrity stained propidium iodide under fl...

Finding a bioactive hybrid material with the potential for controlled drug release has been one of major targets tissue engineering in recent years. In this line, present work describes new approach producing singular hydrogel microparticles (HMPs) different morphologies and compositions by combining experimental computational methods. Calcium-Alginate (Ca-ALG) core–shell Alginate-Chitosan micr...

Hydrogels have been widely investigated as 3D culture substrates because of their reported structural similarity to the extracellular matrix (ECM). Limited ECM deposition, however, occurs within these materials, so the resulting "tissues" bear little resemblance to those found in the body. Here matrix deposition by fibroblasts encapsulated within a calcium alginate (Ca-alg) hydrogel was investi...

The chitosan/alginate-trace element-codoped octacalcium phosphate/nano-sized bioactive glass (CS/ALG-teOCP/nBG) composite membranes were prepared by a layer-by-layer coating method for the functional requirement of guided bone regeneration (GBR). The morphology, mechanical properties and moisture content of the membranes was studied by scanning electron microscopy (SEM) observation, mechanical ...

Natural polyelectrolyte multilayers of chitosan (CHI) and alginate (ALG) were alternately deposited on doxorubicin (DOX)-loaded poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) with layer by layer self-assembly to control drug release for antitumor activity. Numerous factors which influenced the multilayer growth on nano-colloidal particles were studied: polyelectrolyte concentration, ...