OBJECTIVE Although crackles are frequently heard on auscultation of the chest of patients with common cardiopulmonary disorders, the mechanism of production of these sounds is inadequately understood. The goal of this research was to gain insights into the mechanism of crackle generation by systematic examination of the relationship between inspiratory and expiratory crackle characteristics. ...

tracheobronchopathia osteochondroplastica (to) is a rare disorder of large airways with unknown etiology which is characterized by cartilaginous and bony nodules lining the mucosa of the trachea and major bronchi. generally, it is benign and asymptomatic, but it may present with cough, exertional dyspnea and wheezing. it could therefore be mistaken with asthma and chronic obstructive pulmonary ...

Objective(s): Th2 response is related to the aetiology of asthma, but the underlying mechanism is unclear. To address this point, the effect of nebulized inhalation of inactivated Mycobacterium phlei on modulation of asthmatic  airway  inflammation was investigated. Materials and Methods: 24 male BALB/c mice were randomly divided into three groups: control group (Group A), asthma model group (G...

Introdouction: This study investigated the potential relationship between vertical facial growth patterns and airway volumes in a sample of Iranian adult patients. Materials and methods: This cross sectional study was conducted on 72 adult patients (44 females, 28 males), ages 18– 45 years, who had been referred to the Department of Oral and Maxillofacial Radiology at the Shiraz Univer...

BACKGROUND AND OBJECTIVE The mortality rate for patients requiring mechanical ventilation is about 35% and this rate increases to about 53% for the elderly. In general, with increasing age, the dynamic lung function and respiratory mechanics are compromised, and several experiments are being conducted to estimate these changes and understand the underlying mechanisms to better treat elderly pat...

Chronic persistent asthma is characterized by poorly reversible airway obstruction. Histopathological studies of airways removed postmortem from patients with severe asthma reveal marked inflammatory and architectural changes associated with airway wall thickening. Increased airway smooth muscle content, occurring as a result of hyperplastic and/or hypertrophic growth, is believed to be one of ...