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In this paper, we model the associations of childhood health on adult health and socio-economic status outcomes in China using a new sample of middle aged and older Chinese respondents. Modeled after the American Health and Retirement Survey (HRS), the CHARLS Pilot survey respondents are 45 years and older in two quite distinct provinces-Zhejiang, a high growth industrialized province on the Ea...

Transgenic mice over-expressing mutant human amyloid precursor protein (PDAPP mouse) develop several Alzheimer’s disease (AD)-like lesions including an age-related accumulation of amyloid-?-containing neuritic plaques. Although aged, heterozygous PDAPP mice also exhibit synaptic and glial cell changes, that is characteristic of AD pathology, no evidence of neurodegeneration has been observed. T...

This article provides evidence about the quality of retrospective childhood health histories given to respondents in the Health and Retirement Survey (HRS) and the Panel Study of Income Dynamics (PSID). Even though information on early life health events is critical, there is legitimate skepticism about the ability of older respondents to remember specific health problems that they had during c...

A positive association between intelligence (IQ) and height has been reported previously. It is generally assumed that this association reflects the effect of childhood environment on IQ, but there is still little research supporting directly this hypothesis. We studied the association between height and IQ in 209 Dutch twin pairs at the ages of 5, 7, 10 and 12 years, 208 twin pairs at 16 and 1...

Late-onset hypogonadism (LOH) is closely related to secondary androgen deficiency in aged males, but the mechanism remains unclear. In this study, we found that reduced testosterone production in aged rat Leydig cells is associated with decreased autophagic activity. Primary rat Leydig cells and the TM3 mouse Leydig cell line were used to study the effect of autophagic deficiency on Leydig cell...

Many individuals with movement disorders are unable to make efficient use of graphical computer interfaces commonly employed in personal computers. In this study, performance limitations in target tracking with a computer mouse were studied for eight young subjects aged 19 to 29 (M = 23, SD = 3), four old subjects aged 70 to 73 (M = 72, SD = 1), and five motor-disabled subjects aged 37 to 74 (M...

introduction: the most common mode of rabies virus transmission is through a bite wound or contact of broken skin with saliva of a rabid animal. various other routes of virus transmission include exposure of mucous membranes (i.e. eyes, nose, and mouth) to infected saliva of a rabid animal, aerosol transmission, and corneal transplantation. laboratory workers during work with rabies virus and v...