OBJECTIVE We report the findings of Thallium-201 chloride ((201)TlCl) scintigraphy and consider how to use this technique to evaluate the character of soft tissue lesions. PATIENTS AND METHODS We enrolled 91 consecutive patients (45 males and 46 females, age range 8-91-years-old). Nineteen patients were malignant and 72 were benign. Patients were scanned 15 minutes (early phase) and 3 hours (...

OBJECTIVES We sought to determine the prognostic capabilities of exercise thallium (Tl)-201 tomographic imaging performed relatively early (within 2 years) after coronary artery bypass graft surgery (CABG). BACKGROUND Exercise testing is commonly performed after CABG, but few data exist demonstrating its prognostic value in this setting. METHODS Four hundred eleven patients were followed up...

D uring the past 10 years, the use of thallium201 myocardial perfusion imaging has undergone considerable expansion and evaluation. Originally conceived as a noninvasive diagnostic tool useful in determining the presence or absence of anatomical coronary artery disease,1-4 201T1 imaging has now been shown to have important prognostic value in a wide spectrum of patients with coronary artery dis...

PURPOSE To explore the safety and efficacy of PRT-201. METHODS Randomized, double-blind, placebo-controlled, single-dose escalation study of PRT-201 (0.0033 to 9 mg) applied after arteriovenous fistula (AVF) creation. Participants were followed for one year. The primary outcome measure was safety. Efficacy measures were the proportion with intra-operative increases in AVF outflow vein diamete...

Surface area of 201 Japanese (both sexes) from infancy to old age selected statistically by sex, age and body shape were measured and the regional rates calculated and discussed. The results are as follows. 1. There was no difference between either side of the body for age or sex. 2. The rate of head, face and neck decreased while that of the lower extremities increased with aging. 3. After ado...

INTRODUCTION The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates obtained from patients attending a public referral center for sexually transmitted diseases and specialized care services (STD/SCS) in Belo Horizonte, Brazil. METHODS Between March 2011 and February 2012, 201 specimens of Neisseria gonorrhoeae were consecutively obtained from...

We report a method of photo-cross-linking proteins in mammalian cells, which is based on site-specific incorporation of a photoreactive amino acid, p-benzoyl-L-phenylalanine (pBpa), through the use of an expanded genetic code. To analyze the cell signaling interactions involving the adaptor protein Grb2, pBpa was incorporated in its Src homology 2 (SH2) domain. The human GRB2 gene with an amber...

Major changes in arterial pressure, autonomic, and respiratory activity occur in response to hypoxia. We analyzed structural damage and increased vascular permeability in the ventrolateral medulla and nucleus tractus solitarius, which control autonomic, respiratory, and cardiovascular functions in adult Wistar rats subjected to 2 hours of hypoxia (7% oxygen + 93% nitrogen) for up to 14 days aft...

OBJECTIVES We compared dipyridamole technetium-99m (Tc-99m) tetrofosmin and thallium-201 (Tl-201) single-photon emission computed tomographic (SPECT) imaging with respect to the detection rate of perfusion abnormalities in 26 patients with angiographic coronary artery disease (CAD). BACKGROUND Experimental studies have shown that myocardial extraction of Tc-99m tetrofosmin is lower than that ...