a-l-Fetoprotein (AFP) was measured in the sera of 5 hepatoma patients following total hepatectomy and orthotopic liver transplantation. Immunosuppressive therapy, rejection episodes, and infection did not alter the serum level of AFP. Low AFP levels persisting posttransplantation indicated the presence of slow-growing residual tumor in 3 patients. A sharp increase in serum AFP levels preceded c...

A monoclonal immunoenzymometric assay for alpha-fetoprotein (M-AFP) was evaluated with respect to its utility in monitoring hepatocellular carcinoma (HCC) patients. Earlier (Clin Chem 1986;32:1318-22), we found this immunoassay to demonstrate abilities similar to polyclonal AFP assays, and we suggested that changes in M-AFP correlated with changes in intrahepatic tumor volume in most HCC patien...

Plants have evolved protective mechanisms to ensure their survival when threatened by adverse environmental conditions during their transition to autotrophic growth. During germination, there is a 2- to 3-d period during which a plant can execute growth arrest when challenged by water deficit. This postgermination developmental checkpoint is signaled by the stress hormone abscisic acid (ABA), w...

Background: Hepatocellular carcinoma (HCC) is an aggressive deadly cancer with few therapeutic options mostly limited for early-stage HCC. Unfortunately, alphafetoprotein (AFP) has a limited performance, especially in early-stage HCC. Objectives: to investigate plasma levels of Cyclaseassociated protein-2 (CAP2) as a new biomarker and evaluate its role in detecting early-stage and AFP-negative ...

Antigen sequence typing (ST) of FetA is part of the molecular typing scheme of Neisseria meningitidis. Among invasive meningococcal isolates from 2,201 patients in Germany, we identified 11 strains lacking the fetA gene because of deletions mediated by repeat arrays flanking the gene, i.e., Correia elements, repeat sequence 13 (RS13), and duplicated RS3. Geographic mapping and multilocus ST of ...

OBJECTIVES To describe the research methods for the development of a new open source, cross-platform tool which processes data from the European Prospective Investigation into Cancer and Nutrition Norfolk Food Frequency Questionnaire (EPIC-Norfolk FFQ). A further aim was to compare nutrient and food group values derived from the current tool (FETA, FFQ EPIC Tool for Analysis) with the previousl...

Serum alpha fetoprotein (AFP) is the most widely used tumor marker in detecting patients with hepatocellular carcinoma (HCC). However, it has been indicated that HCCR-1 (human cervical cancer oncogene 1) might be supplementary to AFP in the detection. We conducted a prospective study in 120 normal and 524 liver disease patients to evaluate the significance of simultaneous measurement of 2 tumor...

Targeting of proteins to the plasma membrane of cells may be useful for vaccine development, tissue engineering, genetic research, bioseparations, and disease treatment. The ability of different transmembrane domains (TM) to direct a reporter protein (human alpha-feto protein, AFP) to the surface of mammalian cells was examined. High surface expression was achieved with chimeric proteins compos...

In this study, whether the addition of antifreeze protein (AFP) to a cryopreservative solution (plant vitrification 2 (PVS2)) is more effective in reducing freezing injuries Hosta capitata than PVS2 alone at different cold exposure times (6, 24, and 48 h) investigated. The upregulation C-repeat binding factor 1 (CBF1) dehydrin (DHN1) response low temperature was observed shoots. Shoots treated ...

Introduction: AFP, AFP-L3 DCP are useful biomarkers of hepatocellular carcinoma (HCC). However, association between molecular characteristics and serum has not fully evaluated yet. We analyzed RNA expression DNA mutation from TCGA-LIHC data in conjunction with clinical data. Method: Genetic were retrieved portal TCGA. Among total sample 371, we selected 91 samples which could measure using preo...