Little is known of the consequences of divergent selection for residual feed intake (RFI) on intestinal digestion capacity, particularly during immune system stimulation (ISS). Our objective was to evaluate the impact of ISS and divergent selection for RFI on apparent ileal digestibility (AID) and apparent fecal digestibility (AFD) of nutrients and intestinal nutrient active transport and barri...

INTRODUCTION Fabry's disease (AFD) is an X-linked lysosomal storage disease, resulting from a deficiency in alpha-galactosidase A (AGALA). Untreated, this leads to precocious failure of vital organ function and death. As enzyme replacement therapy is available, it is of vital importance that affected individuals can be traced. MATERIALS AND METHODS We set up a screening in the Flemish haemodi...

BACKGROUND In multicellular organisms, cell-cell junctions are involved in many aspects of tissue morphogenesis. α-catenin links the cadherin-catenin complex (CCC) to the actin cytoskeleton, stabilizing cadherin-dependent adhesions. RESULTS To identify modulators of cadherin-based cell adhesion, we conducted a genome-wide RNAi screen in C. elegans and uncovered MAGI-1, a highly conserved prot...

During development, neural activity is important for forming proper connections in neural networks. The effect of activity on the gross morphology and synaptic strength of neurons has been well documented, but little is known about how activity affects different molecular components during development. Here, we examine the localization of four fluorescently-tagged presynaptic proteins, RAB-3, S...

Abstract Background Hypertrophic Cardiomyopathy (HCM) is burdened by sudden cardiac death (SCD) risk of 0.9%/year, and the most common cause SCD in young adults. It an autosomal dominant inherited disease caused mutations sarcomere genes, but hypertrophic phenotype can also be expression involvement multiorgan metabolic storage diseases, such as Anderson-Fabry (AFD). Mechanical Dispersion (MD) ...

La práctica regular de Actividad Física Deportiva (en adelante AFD) tiene efectos beneficiosos a nivel físico y cognitivo. En este segundo nivel, los trabajos recientes, han encontrado mejora en memoria, rendimiento académico, autoestima, atención Funciones Ejecutivas. el presente trabajo corte descriptivo-inferencial participado 110 estudiantes Educación Primaria Secundaria Obligatoria las loc...

Objective: To classify the infants into 9 blocks based on the deviation of both placental weight (PW) and fetal/placental weight ratio (F/P) Z score and compared the incident rate of perinatal death in each of the small for date (SFD) vs. appropriate for date (AFD) vs. heavy for date (HFD) groups. Methods: The study population consisted of 93,034 placentas/infants from women who vaginally deliv...

The current Internet architecture relies on congestion avoidance mechanisms implemented in the transport layer protocols, like TCP, to provide good service under heavy load. If routers distribute bandwidth fairly, the Internet would be more robust and could accommodate more diversity of end hosts. Most of the mechanisms proposed to accomplish this can be grouped into two general categories. The...

Using path-integral Monte Carlo simulations and an ab initio effective Hamiltonian, we study the effects of quantum fluctuations on structural phase transitions in the cubic perovskite compounds SrTiO3 and BaTiO3 . We find quantum fluctuations affect ferroelectric ~FE! transitions more strongly than antiferrodistortive ~AFD! ones, even though the effective mass of a single FE local mode is larg...

Learning from Demonstration (LfD) is a popular technique for building decision-making agents from human help. Traditional LfD methods use demonstrations as training examples for supervised learning, but complex tasks can require more examples than is practical to obtain. We present Abstraction from Demonstration (AfD), a novel form of LfD that uses demonstrations to infer state abstractions and...