نتایج جستجو برای: adult neuron culture

تعداد نتایج: 628180  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Christopher K Thompson Eliot A Brenowitz

Neuron death and replacement are fundamental components of brain plasticity. Much remains unknown, however, about the mechanistic interaction between neuron death and neurogenesis in adult vertebrates. In seasonally breeding adult male white-crowned sparrows, the song system nucleus HVC loses approximately 26% of its neurons via caspase-dependent apoptosis within 4 d after a transition to nonbr...

2012
Carlos Barcia Carmen María Ros Valentina Annese María Angeles Carrillo-de Sauvage Francisco Ros-Bernal Aurora Gómez José Enrique Yuste Carmen María Campuzano Vicente de Pablos Emiliano Fernandez-Villalba María Trinidad Herrero

The role of microglial motility in the context of adult neurodegeneration is poorly understood. In the present work, we investigated the microanatomical details of microglia-neuron interactions in an experimental mouse model of Parkinson's disease following the intraperitoneal injection of MPTP. The specific intoxication of dopaminergic neurons induces the cellular polarization of microglia, le...

Journal: :iranian journal of veterinary medicine 2015
mohammad geranmayeh ali baghbanzadeh abbas barin jamileh salar-amoli mohammad dehghan

background: in vitro model studies are becoming increasingly popular for experimental research designs. they include isolation and expansion of cells of a particular tissue, such as the nervous tissue which contributes to understanding the underlying mechanisms in many pathologies. it enables  the scrutinization of intracellular signaling pathways responsible for cell death. objectives: in the ...

Journal: :Proceedings of International Conference on Artificial Life and Robotics 2019

Journal: :Archives of facial plastic surgery 2011
David M Lieberman Taha A Jan S Omar Ahmad Sam P Most

OBJECTIVES To assess the effects of corticosteroid administration on functional recovery and cell survival in the facial motor nucleus (FMN) following crush injury in adult and juvenile mice and to evaluate the relationship between functional recovery and facial motoneuron survival. METHODS A prospective blinded analysis of functional recovery and cell survival in the FMN after crush injury i...

Journal: :BioTechniques 2005
Lars Eide Cynthia T McMurray

Primary neuronal cells used to model physiology are generally limited to embryonic tissue. However, embryonic tissue is not optimal as a model for age-related changes in physiology or late-onset disease. Successful culturing of neurons from adult animals, however, has been historically difficult, if not impossible. Here, we report methodology for routine and reliable cultivation of healthy stri...

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