We developed a method for simultaneously measuring steroid hormones in very small volumes of serum, using a combination of high-performance liquid chromatography (HPLC) and radioimmunoassay (RIA). By this method, aldosterone, cortisol, 11-deoxycortisol, estrone, estradiol, androstenedione, dehydroepiandrosterone, deoxycorticosterone, 17-hydroxyprogesterone, testosterone, pregnenolone, and proge...

Pure androgen-secreting adrenal adenoma is very rare, and its diagnosis remains a clinical challenge. Its association with resistant hypertension is uncommon and not well understood. We present an 18-year-old female with a 10-year history of hirsutism that was accidentally diagnosed with an adrenal mass during the evaluation of a hypertensive crisis. She had a long-standing history of hirsutism...

Classification of Adrenal Cortical Disorders Lesions of the adrenals frequently cause disturbance of endocrine function. Various clinical syndromes may result, depending on whether the secretion is increased or diminished and, when it is increased, which hormones predominate. The lesions and syndromes may be classified as follows: A. WITH DISTURBANCE OF CORTICAL FUNCTION i. Increased Secretion:...

primary hyperaldosteronism is one of the few causes of hypertension that can be cured by surgery. primary hyperaldosteronism is caused by adrenocortical adenoma or hyperplasia. it is important to differentiate between adrenal adenoma and hyperplasia because the preferred treatments are different. in all patients with new-onest or worsening hypertension the primary hyperaldosteronism should be c...

BACKGROUND Adrenal incidentaloma is an adrenal neoplasm frequently encountered in clinical practice for which detection rates have recently increased. We describe here the clinical characteristics of adrenal incidentalomas. METHODS A retrospective study was performed examining the age, sex, location, size, function, and the histological findings for 348 patients with an adrenal mass discovere...

An adrenal cortical tissue tumor developed in a patient with poorly controlled salt-losing congenital adrenal hyperplasia. A 16-year-old girl became progressively virilized from 13 to 16 years of age. Base line serum progesterone, 17-hydroxyprogesterone, and testosterone levels were high and there was a diurnal pattern of the hormones. Initially elevated urinary 17-ketosteroid and serum steroid...

We report a case of a young hypertensive male who was first seen in 1998 with a right thalamic haemorrhage and uncontrolled hypertension. CT abdomen showed a right adrenal tumour and a hyperplastic left adrenal gland. Laparoscopic adrenalectomy performed followed by histopathological examination confirmed the diagnosis of adrenal adenoma. He subsequently presented to us again a year later with ...

· For pre-pubertal children, and certainly for toddlers, adrenal tumors (e.g. adenoma, carcinoma, or bilateral hyperplasia) are a more common cause of CS. In older children, pituitary adenomas are a more common cause of CS. Ectopic (a site other than pituitary or adrenal) sources of CS are extremely rare in children.Overall, there is a female to male predominance, which decreases with younger age.

We describe the appearance of an adrenal pseudocyst on MRI and CT. The MR characteristics of the lesion were noteworthy in that the lesion had two components with different imaging characteristics. The larger component was of low signal intensity on both T1- and T2-weighted images and might have been confused with an adrenal adenoma.