A considerable body of literature indicates that on monolayer culture, embryonic chick cartilage cells are obtained which morphologically and biochemically behave as chondrocytes (1). Earlier studies suggested that repeated monolayer culture results in "dedifferentiation" of chondro-434 B R I E F N 0 T E S cytes to give fibroblast-like cells. Coon (2) has demonstrated that with appropriate medi...

BACKGROUND/AIMS Altered expression of the integrin family of cell adhesion receptors has been associated with initiation, progression, and metastasis of solid tumors as well as in the development of chemoresistance. Here, we investigated the role of integrins, in particular integrin β1, in cell volume regulation and drug-induced apoptosis in adherent and non-adherent Ehrlich ascites cell lines....

To determine the role marrow-adherent cells may play in the anemia of chronic diseases, marrow samples were collected from ten patients with the anemia of chronic disease, seven control patients with cancer but without the anemia of chronic disease, and five normal volunteers. Marrow was either cultured directly or first depleted of adherent cells and then cultured. Plasma clots containing 6 X ...

OBJECTIVE To develop and evaluate a multiprofessional modular medication management to assure adherence to capecitabine. METHODS The study was conducted as a prospective, multicentred observational cohort study. All participants received pharmaceutical care consisting of oral and written information. Daily adherence was defined as percentage of days with correctly administered capecitabine do...

The proliferative response of mouse B lymphocytes induced by Fc fragments was found to be dependent upon an adherent cell population. The adherent cell is esterase positive, irradiation resistant, and not susceptible to lysis by anti-thymus serum and complement. The mechanism(s) by which Fc fragments induce B-cell proliferation could be the result of the interaction of Fc with both B cells and ...

E-commerce is growing rapidly and sales of digital goods represent a substantial portion of all online sales. Several goods such as music and books are now available in a physical and digital format. In a single-period case we compare pricing of digital vs. physical goods and derive an optimal pricing strategy for digital goods in both a general setting without a capacity constraint and a capac...

OBJECTIVES To identify the incidence of morbidly adherent placenta in the context of a rising caesarean delivery rate within a single institution in the past 15 years, and to determine the contribution of morbidly adherent placenta to the incidence of massive postpartum haemorrhage requiring hysterectomy. SETTING A regional obstetric unit in Hong Kong. PATIENTS Patients with a morbidly adhe...

One of the most unique physical features of cell adhesion to external surfaces is the active generation of mechanical force at the cell-material interface. This includes pulling forces generated by contractile polymer bundles and networks, and pushing forces generated by the polymerization of polymer networks. These forces are transmitted to the substrate mainly by focal adhesions, which are la...