Objective: Reducing white adipose tissue is an important strategy for treatment of obesity and its related metabolic disorders. The purpose of this study was to determine the effect of endurance exercise and adenosine consumption on the expression of selected genes of thermogenic pathway in the visceral adipose tissue of obese male rats. Materials and Methods: Twenty male wistar rats were fed ...

introduction vincent’s angina refers to acute necrotizing ulcerative lesions of the oral mucosal membranes and tonsils. case presentation; in this case, we report a 17-year old girl with emotional stress referred with symptoms of vincent’s angina. gram staining showed numerous fusospirochetal bacteria. with antibiotic therapy, amoxicillin and cephalexin, no clinical improvement was observed but...

conclusions caffeine has a potential role for pain modulation. current evidence on caffeine use for migraine and terminal stage cancer is not well-established. future studies should address the use of caffeine alone for different types of pain with dose escalation and standardization of outcome measurement. evidence acquisition the data on caffeine as an adjuvant therapy or as a main component ...

recent reports have suggested that cytomegalovirus (cmv) infection may contribute to risk of cardiovascular disease. however, relationship between cmv infection and unstable angina (ua) is controversial and studies about this subject in iran and even region are lacking. the aim of this study was to determine whether unstable angina is related to seropositivity to chronic cytomegalovirus infecti...

Purpose: To determine the efficacy and safety of a combination ulinastatin meglumine cyclic adenosine monophosphate (cAMP) in treatment acute myocardial infarction (AMI), its effect on serum levels hypersensitive-c-reactive protein (hs-CRP), cardiac troponin I (cTnI), creatine kinase (CK).Methods: A total 90 AMI patients admitted to The Second Affiliated Hospital Qiqihar Medical College, City, ...

Introduction: Ligands of adenosine A1Rs are potential candidates for the development drugs treatment paroxysmal supraventricular tachycardia, angina pectoris, hypertriglyceridemia, type 2 diabetes mellitus, neuropathic pain, and heart failure. At same time, there is a deficiency that can regulate functions A1 receptors. A number A1-antagonists at various stages clinical trials; other not very s...

BackgroundCoronary vasomotor dysfunction, comprising endotypes of coronary spasm and/or impaired microvascular dilatation (IMD), is common in patients with angina and no obstructive arteries (ANOCA). However, there are discrepant reports regarding the prevalence these endotypes. The objective this study was to determine dysfunction ANOCA, underlying endotypes, differences clinical characteristi...

Summary: Adenosine through adenosine receptor have a crucial role in biology of lung cancer. Recent study indicated adenosine receptors have a crucial role in various aspect of lung cancer from cell growth and metastasis to modulation of apoptosis and it could be considered as a potential candidate for treatment of the lung cancer.