The aim of this study was to develop a diagnostic tool capable of providing diffusion and apparent diffusion coefficient (ADC) map information in a single color-coded image and to assess the performance of color-coded images compared with their corresponding diffusion and ADC map. The institutional review board approved this retrospective study, which sequentially enrolled 36 head MRI scans. Di...

The objective of this study was to examine the tumor spatial heterogeneity in myxoid-containing soft-tissue tumors (STTs) using texture analysis of diffusion-weighted imaging (DWI). A total of 40 patients with myxoid-containing STTs (23 benign and 17 malignant) were included in this study. The region of interest (ROI) was manually drawn on the apparent diffusion coefficient (ADC) map. For textu...

PURPOSE The aim of this study was to map the disease locus of autosomal dominant cataracts (ADC) in a Chinese family. METHODS A four-generation family with multiple individuals affected by ADC was investigated. Genomic DNA was collected from 22 family members. A gene-scan at known candidate ADC loci was performed. To achieve fine-mapping we genotyped fourteen STR markers at the critical regio...

UNLABELLED Non-echoplanar diffusion weighted magnetic resonance imaging (DWI) has established itself as the modality of choice in detecting and localising post-operative middle ear cleft cholesteatoma. Despite its good diagnostic performance, there are recognised pitfalls in its radiological interpretation which both the radiologist and otologist should be aware of. Our article highlights the v...

Objective: The aim of this study was to evaluate the role of diffusion-weighted magnetic resonance imaging (dMRI) in differentiating between diffuse malignant and benign pleural thickening in asbestos-related pleural diseases. Materials and Methods: Sixty-two patients were included in the study. Thirty-two had a benign form and 30 had malignant pleural mesothelioma (MPM). The patient files and ...

We describe a novel MRI technique, detecting metabolism indirectly through changes in oxyhemoglobin: deoxyhemoglobin ratios and T2* signal change during “oxygen challenge” (OC, 5 mins 100% O2). During OC, T2* increase reflects O2 binding to deoxyhemoglobin, formed when metabolizing tissues take up oxygen. Here OC has been applied to identify tissue metabolism within ischemic brain. Permanent MC...

PURPOSE To present comprehensive examinations of the assumptions made in functional diffusion map (fDM) analyses and provide a biological basis for fDM classification. MATERIALS AND METHODS Sixty-nine patients with gliomas were enrolled in this study. To determine the sensitivity of apparent diffusion coefficients (ADCs) to cellularity, cell density from stereotactic biopsy specimens was corr...

Objective: Our aim is to investigate the predictive value of diffusion-weighted magnetic resonance imaging (DW-MRI) and apparent diffusion coefficient (ADC) values in cervical lymph node metastasis from nasopharyngeal carcinoma (NPC) after chemoradiatherapy. Methods: Between March 2010 and January 2013, 71 patients diagnosed with NPC were selected in our study. All patients received conventiona...

results a low adc value was associated with lymph node metastasis (p < 0.01) and with high ki-67 protein levels (p = 0.03). there were no significant differences in the adc values among the histological grade (p = 0.48), molecular subtype (p = 0.51), tumor size (p = 0.46), and p53 protein level (p = 0.62). conclusion the pre-operative use of the 3.0 tesla dwi could provide information about the...

OBJECTIVE Permeability parameters from dynamic contrast-enhanced MRI (DCE-MRI) and apparent diffusion coefficient (ADC) value on diffusion-weighted imaging (DWI) can be quantitative physiologic metrics for gliomas. The transfer constant (K(trans)) has shown efficacy in grading gliomas. Volume fraction of extravascular extracellular space (ve) has been underutilized to grade gliomas. The purpose...