Since its discovery in 1999, ghrelin has been implicated in a multiplicity of physiological activities. Most notably, ghrelin has an important influence on energy metabolism and after the identification of its potent appetite stimulating effects ghrelin has been termed the 'hunger hormone'. Exercise is a stimulus which has a significant impact on energy homeostasis and consequently a substantia...

BACKGROUND Ghrelin is a 28-amino acid peptide with an orexigenic property, which is predominantly produced by the stomach. Acylated ghrelin is the active form of this hormone. Obestatin is a 23-amino acid peptide which is produced by post-translational modification of a protein precursor that also produces ghrelin. Obestatin has the opposite effect of ghrelin on food intake. The aim of this stu...

BACKGROUND We investigated whether ghrelin is present in human saliva, is produced by salivary glands, and physiologic consequences of these findings. METHODS Expression of ghrelin and specific receptor mRNA was determined by PCR. Proteins were identified by immunoblotting and size-exclusion fast protein liquid chromatography (FPLC) with consecutive RIA. Specific RIAs were used for quantifica...

The croaker Cilus gilberti commonly known as Corvina drum is considered a target marine species for the diversification of Chilean aquaculture. To optimize culture conditions, molecular markers appetite regulation must be examined. Ghrelin, gastrointestinal peptide, plays stimulatory role in food intake mammals and teleost fish. Nevertheless, even though appetite-controlling system relatively w...

PURPOSE To explore whether compensatory responses to acute energy deficits induced by exercise or diet differ by sex. METHODS In experiment one, 12 healthy women completed three 9-h trials (control, exercise-induced (Ex-Def) and food restriction-induced energy deficit (Food-Def)) with identical energy deficits being imposed in the Ex-Def (90-min run, ∼70% of V˙O2max) and Food-Def trials. In e...

PURPOSE This study examined the effect of an acute bout of brisk walking on appetite, energy intake, and the appetite-stimulating hormone-acylated ghrelin. METHODS Fourteen healthy young males (age 21.9 +/- 0.5 yr, body mass index 23.4 +/- 0.6 kg x m(-2), (.)VO2max 55.9 +/- 1.8 mL x kg(-1) x min(-1); mean +/- SEM) completed two 8-h trials (brisk walking and control) in a randomized counterbal...

OBJECTIVE Recently published animal studies indicate that leptin and ghrelin play a role in puberty initiation and progress as well as in reproduction. The aim of our study was to evaluate the relation of these two hormones to the pubertal maturity and fertility status in patients with beta-thalassemia. DESIGN Blood levels of leptin, acylated ghrelin and sex hormones were determined in 97 (59...

Ghrelin, a 28-amino acid acylated peptide, was identified as the endogenous ligand for the growth hormone (GH) secretagogue receptor and its role in reproduction has recently been established. It is believed that the site of ghrelin expression in testes may indicate its role in local regulation. This study investigated the immunohistochemical (IHC) localization of ghrelin in Holstein bull testi...

Stress, mood, and eating behavior play an important role in appetite weight regulation. In particular, ghrelin, as the only known orexigenic hormone, has been suggested to be influential mediator food intake responses stress. The exact of ghrelin hypothalamic–pituitary–adrenal axis is still unknown further challenged by psychological aspects stress behavior. This study aimed assess effect chron...

The effects of feeding corn or rice, either raw or heat processed (HP), on apparent total tract digestibility (ATTD) and apparent ileal digestibility (AID) of nutrients and on insulin and ghrelin concentrations in the serum were studied in young pigs. Pigs were weaned at approximately 23 ± 3 d of age and weighed 7.4 ± 1.2 kg. Each of the 4 treatments was replicated 9 times, and the experimental...