Transfusion-related acute lung injury (TRALI) is a serious adverse reaction of transfusion, and presents as hypoxemia and non-cardiogenic pulmonary edema within 6 hours of transfusion. A 14-year-old primigravida woman at 34 weeks of gestation presented with upper abdominal pain without dyspnea. Because she showed the syndrome of HELLP (hemolysis, elevated liver enzymes, and low platelet count),...

Background: Many of the multiple traumatized patients who refer to the hospital need transfusion. Transfusion-related acute lung injury (TRALI) is a serious clinical syndrome associated with the transfusion of plasma-containing blood components. In the article, we present a case of TRALI following transfusion of packed red blood cells Case Presentation: A 24 year old male referred to Shahid Beh...

Transfusion therapy is a key intervention in decreasing morbidity and mortality in patients with sickle cell disease (SCD). Current indications for acute and chronic transfusion therapy have significantly increased the number of RBC units transfused to patients with SCD worldwide. This review summarizes transfusion management for the treatment or prevention of neurologic and perioperative compl...

The spectrum of adverse reactions to blood product transfusion ranges from a benign clinical course to serious morbidity and mortality. There have been many advances in technologies and transfusion strategies to decrease the risk of adverse reactions. Our aim is to address a few of the advancements in increasing the safety of the blood supply, specifically pathogen reduction technologies, bacte...

There is an increasing demand for platelet transfusions due to intensive chemotherapy and blood stem cell or bone marrow transplantation for the treatment of hematologic and oncologic diseases. There has been a long-lasting debate over whether the traditional threshold for prophylactic platelet transfusion of 20,000/microl is really necessary to prevent hemorrhagic complications. During the las...

The relevance of this paper is that transfusion allogeneic blood to recipient animals always associated with immunological risks. In regard, the purpose study was assess state phagocytic activity neutrophils by indicators index, number, and oxygen-dependent bactericidal activity, as well establish changes in antibody-dependent cytotoxic lymphocytes rabbits during whole transfusion. Modelling tr...

A lthough anaphylactic transfusion reactions due to underlying immunoglobulin A deficiency (IgAD) are rare, it is not uncommon for transfusion medicine physicians to encounter patients with transfusion reactions with respiratory distress or hypotension, where the specter of anaphylaxis is raised. In such cases, IgAD with associated anti-IgA as the underlying cause must be excluded. Another comm...