Acute kidney injury (AKI) is common in hospital patients and more so in critically ill patients. It is frequent, harmful and potentially treatable condition. In a total of 243 renal biopsies 130 cases fulfilled the criteria of acute kidney injury. The usual mode of presentation was renal failure followed by acute nephritis. Histopathologically acute interstitial nephritis was the usual finding ...

Novel biomarkers can be suitable for early acute kidney injury diagnosis and the prediction of the need for dialysis. It remains unclear whether such biomarkers may also play a role in the prediction of recovery after established acute kidney injury or in aiding the decision of when to stop renal support therapy. PubMed, Web of Science and Google Scholar were searched for studies that reported ...

1 Gulhane Military Medical Academy Department of Nephrology, Ankara, Turkey 2 Gulhane Military Medical Academy, Department of Internal Medicine Ankara, Turkey aBSTRaCT aım: Elderly patients with renal disease have recently attracted increased attention. There has also been an increase in renal biopsies in these patients. The aim of this study was to investigate the influence of the renal biopsy...

Marked hyperuricemia is known to cause acute renal failure via intrarenal crystal deposition. However, recent studies suggest mild hyperuricemia may have vasoactive and proinflammatory effects independent of crystal formation. We therefore tested the hypothesis that mild hyperuricemia might exacerbate renal injury and dysfunction in a model of cisplatin-induced acute renal failure in the rat. C...

to delineate the incidence , epidemiology, etiology, and prognosis of acute renal failure (arf) and to compaed the findings with international data, we prospectively studied 2360 patients, admitted at shariati hospital during a four months period ending on jan, 6, 1996. one hundred and twenty-four (5.1%) patients meeting arf crieteria were encountered. the most common cause of arf was prerenal ...

BACKGROUND AND OBJECTIVES The prescription and delivery of renal replacement therapy for acute kidney injury is subject to a wide variation and is conditioned by a multiplicity of factors. A variety of renal replacement therapy modalities are now available to treat acute kidney injury; however, there are no standards for the dosage, choice of modality, and intensity and duration of these therap...

Hydrogen (H2), a new antioxidant, was reported to reduce (•)OH and ONOO(-) selectively and inhibit certain proinflammatory mediators to product, without disturbing metabolic redox reactions or ROS involved in cell signaling. We herein aim to explore its protective effects on acute renal injury in sodium taurocholate-induced acute pancreatitis and its possible mechanisms. Rats were injected with...

Penetrating injuries to the duodenum can present a complex case for trauma or acute care surgeons. The associated and complications have devastating results. This report presents of 41-year-old male who presented with gunshot wound his abdomen suffered gastric injury, transverse colon duodenal renal pancreatic tail injury. In this case, patient underwent Roux-en-Y reconstruction. had good outco...

Telomeres of most somatic cells progressively shorten, compromising the regenerative capacity of human tissues during aging and chronic diseases and after acute injury. Whether telomere shortening reduces renal regeneration after acute injury is unknown. Here, renal ischemia-reperfusion injury led to greater impairment of renal function and increased acute and chronic histopathologic damage in ...