Keane and Freedman (1) demonstrated that diuresis produced by feeding 5% glucose rendered mice susceptible to acute ascending pyelonephritis with Escherichia coli. We reported the use of this model in therapeutic studies of E. coli (2) and Proteus mirabilis (3) pyelonephritis. The present investigation, a bacteriologic, immunologic, and pathologic study of long-term infection with E. coli shows...

Emphysematous pyelonephritis is a rare life-threatening condition caused by a severe acute necrotising infection of the renal parenchyma and its perinephric tissues, and it is commonly seen in diabetic patients. There is a rare association between emphysematous pyelonephritis and hepatic portal venous gas. Hepatic portal venous gas is an uncommon radiological finding, which implies a significan...

In 1956, West and Zimmerman reported a 'first case' of haemolytic anaemia, apparently caused by the use of nitrofurantoin (Furadantin). Since then, no further reports of this untoward effect of the drug have appeared in the literature. Recently a case of acute pyelonephritis treated with Furadantin, observed in the Paediatric Department of the Poriah Government Hospital in Tiberias, developed s...

Bone morphogenetic protein 7 (BMP- 7) is a member of the transforming growth factor (TGF) beta superfamily and is involved in regeneration, repair, and development of specific tissues, for example kidney and skeleton. The experimental studies have shown its protective role against fibrotic processes. Tubulointerstitial changes are present in the pyelonephritic kidney which progresses to fibrosi...

The incidence of cystitis is much higher than that of pyelonephritis. Uncomplicated UTIs are episodios of acute cystitis or pyelonephritis when it occurs in a healthy premenopausal, non-pregnant woman with no known urological abnormalities (structural or functional) [1-5]. UTI that do not meet these criteria is considered complicated. This review is focused on management of acute uncomplciated ...

A case of subcapsular hematoma, a rare complication of acute pyelonephritis (APN) is described. A 60-year-old diabetic woman was admitted with a 3 day history of fever and left flank pain due to acute pyelonephritis. On the third day in hospital, left flank pain worsened despite use of antibiotics available for the treatments of APN and hemoglobin rapidly decreased from 11.1 to 7.9 g/dL. Ultras...

OBJECTIVE To compare the short-term effectiveness of ceftriaxone single dose followed by cefixime with a standard treatment of acute uncomplicated pyelonephritis in women. METHODS An open, prospective, and randomised trial of women with acute uncomplicated pyelonephritis was performed. Group A were given a daily intravenous dose of 1 g ceftriaxone; group B: ceftriaxone 1 g intravenous single ...

Acute pyelonephritis is one of the most common indications for antepartum hospitalization, estimated at approximately 9.7% all predelivery and when diagnosed, conventional treatment includes intravenous fluid parenteral antibacterial administration, careful monitoring balance. Here, we present four cases acute in pregnancy treated patient successfully delivered with healthy babies.

OBJECTIVES To evaluate the role of primary vesicoureteral reflux (VUR) in increasing the frequency and severity of urinary tract infections (UTIs) and renal parenchymal damage among patients with acute pyelonephritis and to determine whether urinary antibiotic prophylaxis reduces the frequency and/or severity of UTIs and/or prevents renal parenchymal damage among patients with mild/moderate VUR...