Abstract Background Polycythemia vera (PV) is characterized by red cell mass expansion in the peripheral blood and can be complicated with thrombosis, bleeding, evolution to acute myeloid leukemia (AML) or a fibrotic phase. Paroxysmal nocturnal hemoglobinuria (PNH) an acquired clonal haematopoietic stem disorder associated chronic intravascular hemolysis, venous defective hematopoiesis, frequen...

Platelet adherence surrounding leucocytes in a rosette formation or platelet satellitism is a rare phenomenon. This finding has been observed almost exclusively in Ethylenediaminetetraacetic acid treated blood at room temperature. The mechanism underlying this phenomenon is not fully understood. In many reports of platelet satellitism platelets clump to polymorphonuclear neutrophils in healthy...

Russell’s viper and hump-nosed are deadly venomous Viperidae snakes in Sri Lanka. Both these vipers widely distributed all climatic zones of the island. causes systemic envenoming such as coagulopathy, neuroparalysis acute kidney injury (AKI) whilst frequently local rarely AKI coagulopathy. These two may cause atypical syndromes like thrombotic microangiopathy (TMA) hemolytic uremic syndrome (H...

OBJECTIVE We present a rare case of pernicious anemia presented as multi-organ dysfunction syndrome, later found to have pseudo-thrombotic thrombocytopenic purpura. METHODS An 86-year-old female presented with respiratory distress, altered mental status, acute renal failure and was intubated in emergency room. She was found to have severe anemia, thrombocytopenia, high lactate, high lactate d...