Brucellosis is a highly contagious zoonosis affecting livestock and human beings. The human disease lacks pathognomonic symptoms and laboratory tests are essential for its diagnosis. However, most tests are difficult to implement in the areas and countries were brucellosis is endemic. Here, we compared the simple and cheap Rose Bengal Test (RBT) with serum agglutination, Coombs, competitive ELI...

BACKGROUND The objectives of this systematic review, commissioned by WHO, were to assess the frequency and severity of clinical manifestations of human brucellosis, in view of specifying a disability weight for a DALY calculation. METHODS/PRINCIPAL FINDINGS Thirty three databases were searched, with 2,385 articles published between January 1990-June 2010 identified as relating to human brucel...

    Human brucellosis is common in developing countries and is a multi-system disease with a broad spectrum of clinical manifestations. Cutaneous lesions associated with brucellosis have been rarely reported in the literature. Here we present a case of a 32-year-old man with history of consumption of cheese made from raw milk seen with occurrence of pancytopenia and diffuse maculopapular rash...

The results of seven serologic tests for diagnosis of human brucellosis were evaluated. The titrated Rose Bengal test, microagglutination test, microtiter-adapted Coombs test, and immunocapture-agglutination test (Brucellacapt) were positive for all sera from patients with acute brucellosis. The immunoglobulin G (IgG), IgM, and IgA commercial enzyme immunoassays (ELISAs) failed to show specific...

BACKGROUND Brucellosis may cause serious infections in healthy individuals living in countries that are endemic for the infection. However, reports of brucella infections in immunocompromised hosts are relatively rare. CASE PRESENTATIONS Reported here are two patients with acute leukemia who developed Brucella melitensis bacteremia during their follow up at the Armed Forces Hospital in Riyadh...

Winchester, UK) collected 12 days after fever onset was positive. Antimicrobial drug treatment was changed to doxycycline and gentamicin. However, low-grade fever and low back pain developed 2 days after administration of gentamicin. The back pain was attributed to muscle pain and was almost completely relieved by 2-day treatment with a nonsteroidal antiinfl ammatory drug. Whole-body gallium sc...

background: brucellosis is the major bacterial zoonoses of global importance caused by brucella spps. fcγriia receptor plays a central role in phagocytosis of igg2-opsonized bacteria. fcγriia exhibits allelic polymorphisms with different capacities for binding igg2 and phagocytosis. cells expressing fc γ riia-h131, bind more efficiently to complexes of igg2 than those expressing the fc γ rii a ...

Brucellosis is a zoonotic disease common in developing countries. Vascular complications, including arterial and venous, associated with Brucella infection have rarely been reported. A case of deep venous thrombosis (DVT) developing after a diagnosis of acute brucellosis in a young milkman is presented. A 26-year-old man presented with pain in the right leg. The patient's medical history includ...

Brucellosis is an endemic zoonotic disease in Saudi Arabia. Accurate diagnosis of brucellosis is made by the isolation of Brucella species, but this is achieved only in 40 to 70% of cases (4). Therefore, laboratory diagnosis of brucellosis is made by demonstration of high levels of Brucella antibodies with the standard agglutination test (SAT) (2). We conducted a study to monitor Brucella antib...

Brucellosis is considered a zoonotic disease which is still an important health problem in endemic areas such as the Middle East, the Mediterranean, and Asia. Brucellosis is a sys‐ temic infection that might affect any organ or system in the body. Ocular involvement has been reported in 21% of brucellosis patients. The most common ocular manifestations of brucellosis were considered as anterior...